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Table 2 Statistical analysis of the variation of the magnitude of the internal motion vector within the tumor, the variation of the target coverage (indicated by the V95CTV parameter), the dose homogeneity (HCTV), average of the variation of the number of particles per IES (\( \overline{\overline{\upsigma \mathrm{np}}\ } \)) and Modulation Index (MIplan). The values presented correspond to the mean, standard deviation (std.) and the two extreme cases (minimum and maximum) for the set of plans and patients. Each of these parameter was between each other correlated, the Pearson correlation coefficient (r) and the significance p-value are presented. Correlations with p-values below 0.05 were considered not significant (n.a.)

From: Significance of intra-fractional motion for pancreatic patients treated with charged particles

Parameter Mean ± std. Min. Max. Correlation Parameter r
(p-value)
Internal Motion
vector magnitude
(mm)
5.2 ± 2.7 2.2 (H15) 12.7 (H12) Std. ∆V95 0.86 (<  0.05)
Std. ∆HCTV 0.77
(< 0.05)
∆V954DDSim + 4DDReco (%) −6.9 ± 7.0 1.2 ± 1.0 (H11) −20.9 ± 3.9 (H7) \( \overline{\upsigma \mathrm{np}} \) n.a.
(> 0.05)
MI n.a.
(> 0.05)
MI*motion 0.76
(< 0.05)
∆HCTV4DDSim + 4DDReco (%) 11.7 ± 8.9 0.6 ± 1.0 (H11) 30.0 ± 5.9 (H12) \( \overline{\upsigma \mathrm{np}} \) n.a.
(> 0.05)
MI n.a
(> 0.05)
MI*motion 0.75
(< 0.05)
\( \overline{\upsigma \mathrm{np}} \) 1.7 ± 0.4 1.1 (H13) 2.6 (H8)
MI 11.2 ± 6.2 3.0 (H14) 22.5 (H11)