Characteristic | Patients |
---|---|
Sex | |
Male | 14 (70%) |
Female | 6 (30%) |
Median age (range) | 61 years (26–79) |
Age < 50 years | 6 (30%) |
Median follow-up [months], 95%-CI | 31.0 (20.1–42) |
Surgery pre-RT | 14 (70%) |
Gross total resection | 10 (50%) |
Subtotal | 3 (15%) |
Debulking | 1 (5%) |
Simpson grade of resection | |
I | 9 (45%) |
II | 1 (5%) |
III | 0 |
IV | 3 (15%) |
V | 1 (5%) |
Recurrence patterns | |
No recurrence | 16 (80%) |
In-field recurrence | 3 (15%) |
Marginal recurrence | 0 |
Ex-field recurrence | 1 (5%) |
Median dose of RT [Gy] | 60 (59.4–60.0) |
Median interval between PET-scan and RT [months] | 1.3 (0–9) |
WHO grade | |
II | 16 (80%) |
III | 4 (20%) |
Localization | |
Frontal | 14 (70%) |
Frontoparietal | 3 (15%) |
Frontotemporal | 1 (5%) |
Parietooccipital/occipital | 2 (10%) |
Technique | |
Step-and-shoot-IMRT (# SIB) | 18 (90%)/6 (SIB) |
3D | 2 (10%) |
Median safety margin GTV → CTVhom or CTVext | 15 mm (2–20 mm) |
Median safety margin CTV → PTVhom or PTVext [mm] | 4 (2–7) |
Median safety margin GTV → PTVboost [mm] | 3 (0–10) |
Mean GTV size [ml] | 64.5 (14.8–192.7) |
Mean PTV size [ml] | |
PTVext or PTVhom | 301.5 (83.7–743.0) |
PTVboost | 190.3 (20.5–586.2) |