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Table 4 Treatment period

From: Clinical outcome of elderly patients (≥ 70 years) with esophageal cancer undergoing definitive or neoadjuvant radio(chemo)therapy: a retrospective single center analysis

 

Before 2008

After 2008

 

n

%

n

%

p-value

Gender

 male

22

88

23

77

0.318

 female

3

12

7

23

 

Age

  < median (75 yrs)

8

32

15

50

0.178

  ≥ median

17

68

15

50

 

Charlson score

  ≤ 1

15

60

25

83

0.053

  > 1

10

40

5

17

 

Histology

 SCC

14

56

27

90

0.04

 Adenocarcinoma

11

44

3

10

 

Localization

 Cervical

2

8

3

10

0.964

 Upper thoracic

5

20

7

23

 

 Middle throacic

9

36

11

37

 

 Lower thoracic

9

36

9

30

 

Grading

 G2

13

52

17

57

0.580

 G3

12

48

12

40

 

T stage

 T1–3

17

68

27

90

0.042

 T4

8

32

3

10

 

N stage

 N0

11

44

12

40

0.765

 N+

14

56

18

60

 

PET-CT Staging

 yes

6

24

30

100

< 0.001

 no

19

76

0

0

 

RT sequence

 Neoadjuvant

1

4

6

20

0.112

 Definitive

24

96

24

80

 

RT technique

 3D-CRT

25

100

25

83

0.056

 IMRT

0

0

5

17

 

Chemotherapy

 yes

19

76

28

93

0.123

 no

6

24

2

7

 

Treatment field

  < 20 cm

7

28

18

60

0.033

  ≥ 20 cm

16

64

12

40

 
  1. yrs years, SCC squamous cell carcinoma, PET-CT positron emission tomography with computed tomography, RT radiation therapy, 3D-CRT three-dimensional conformal radiation therapy, IMRT intensity-modulated radiation therapy, cm centimeters