Table 3 Summary of the dosimetric parameters from the investigated techniques of PTVs, OARs and MUs
Item | Parameter | General MCO-VMAT | APMCO-VMAT | p value |
|---|---|---|---|---|
PTV70 | D98% (Gy) | 69.5 ± 0.3 | 69.4 ± 0.5 | 0.66 |
|  | D2% (Gy) | 74.7 ± 0.9 | 74.9 ± 0.9 | 0.11 |
|  | CN | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.50 |
PTV59.4 | D98% (Gy) | 58.1 ± 0.7 | 58.3 ± 0.7 | 0.09 |
|  | D2% (Gy) | 74.0 ± 0.6 | 74.1 ± 0.6 | 0.29 |
|  | CN | 0.5 ± 0.0 | 0.5 ± 0.1 | 0.89 |
PTV54 | D98% (Gy) | 53.2 ± 0.9 | 53.0 ± 0.8 | 0.31 |
|  | D2% (Gy) | 60.0 ± 0.9 | 60.1 ± 0.9 | 0.64 |
|  | CN | 0.2 ± 0.0 | 0.2 ± 0.0 | 0.15 |
Brainstem | D2% (Gy) | 51.1 ± 2.1 | 50.9 ± 2.3 | 0.59 |
Spincal cord | D2% (Gy) | 42.1 ± 1.8 | 41.8 ± 1.9 | 0.31 |
Left optic nerve | D2% (Gy) | 46.2 ± 6.8 | 46.3 ± 7.0 | 0.74 |
Right optic nerve | D2% (Gy) | 45.7 ± 7.4 | 45.2 ± 7.5 | 0.13 |
Chiasm | D2% (Gy) | 41.8 ± 8.7 | 41.5 ± 9.4 | 0.67 |
Left len | D2% (Gy) | 6.1 ± 1.0 | 6.1 ± 1.1 | 0.77 |
Right len | D2% (Gy) | 6.1 ± 1.0 | 6.1 ± 1.1 | 0.93 |
Left parotid gland | V30 (%) | 42.1 ± 5.6 | 42.7 ± 2.5 | 0.17 |
|  | Dmean (Gy) | 31.8 ± 1.7 | 31.2 ± 4.0 | 0.41 |
Right parotid gland | V30 (%) | 42.5 ± 2.7 | 42.7 ± 2.9 | 0.24 |
|  | Dmean (Gy) | 31.2 ± 3.9 | 31.9 ± 1.7 | 0.16 |
Left temporal lobe | D2% (Gy) | 63.2 ± 6.3 | 63.5 ± 6.7 | 0.34 |
Right temporal lobe | D2% (Gy) | 64.5 ± 5.7 | 64.9 ± 5.7 | 0.36 |
Oral cavity (excluding PTV’s) | Dmean (Gy) | 39.9 ± 2.7 | 39.7 ± 3.1 | 0.35 |
Glottic larynx | Dmean (Gy) | 50.9 ± 3.3 | 45.6 ± 3.3 | < 0.0001 |
Submandibular glands | Dmean (Gy) | 55.1 ± 1.8 | 54.9 ± 2.1 | 0.55 |
Pharyngeal constrictor muscles | Dmean (Gy) | 53.8 ± 1.4 | 49.3 ± 1.4 | < 0.0001 |
MU |  | 505.6 ± 40.5 | 510.5 ± 34.3 | 0.09 |