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Table 3 Summary of the dosimetric parameters from the investigated techniques of PTVs, OARs and MUs

From: A new strategy for volumetric-modulated arc therapy planning using AutoPlanning based multicriteria optimization for nasopharyngeal carcinoma

Item Parameter General MCO-VMAT APMCO-VMAT p value
PTV70 D98% (Gy) 69.5 ± 0.3 69.4 ± 0.5 0.66
  D2% (Gy) 74.7 ± 0.9 74.9 ± 0.9 0.11
  CN 0.6 ± 0.1 0.6 ± 0.1 0.50
PTV59.4 D98% (Gy) 58.1 ± 0.7 58.3 ± 0.7 0.09
  D2% (Gy) 74.0 ± 0.6 74.1 ± 0.6 0.29
  CN 0.5 ± 0.0 0.5 ± 0.1 0.89
PTV54 D98% (Gy) 53.2 ± 0.9 53.0 ± 0.8 0.31
  D2% (Gy) 60.0 ± 0.9 60.1 ± 0.9 0.64
  CN 0.2 ± 0.0 0.2 ± 0.0 0.15
Brainstem D2% (Gy) 51.1 ± 2.1 50.9 ± 2.3 0.59
Spincal cord D2% (Gy) 42.1 ± 1.8 41.8 ± 1.9 0.31
Left optic nerve D2% (Gy) 46.2 ± 6.8 46.3 ± 7.0 0.74
Right optic nerve D2% (Gy) 45.7 ± 7.4 45.2 ± 7.5 0.13
Chiasm D2% (Gy) 41.8 ± 8.7 41.5 ± 9.4 0.67
Left len D2% (Gy) 6.1 ± 1.0 6.1 ± 1.1 0.77
Right len D2% (Gy) 6.1 ± 1.0 6.1 ± 1.1 0.93
Left parotid gland V30 (%) 42.1 ± 5.6 42.7 ± 2.5 0.17
  Dmean (Gy) 31.8 ± 1.7 31.2 ± 4.0 0.41
Right parotid gland V30 (%) 42.5 ± 2.7 42.7 ± 2.9 0.24
  Dmean (Gy) 31.2 ± 3.9 31.9 ± 1.7 0.16
Left temporal lobe D2% (Gy) 63.2 ± 6.3 63.5 ± 6.7 0.34
Right temporal lobe D2% (Gy) 64.5 ± 5.7 64.9 ± 5.7 0.36
Oral cavity (excluding PTV’s) Dmean (Gy) 39.9 ± 2.7 39.7 ± 3.1 0.35
Glottic larynx Dmean (Gy) 50.9 ± 3.3 45.6 ± 3.3 < 0.0001
Submandibular glands Dmean (Gy) 55.1 ± 1.8 54.9 ± 2.1 0.55
Pharyngeal constrictor muscles Dmean (Gy) 53.8 ± 1.4 49.3 ± 1.4 < 0.0001
MU   505.6 ± 40.5 510.5 ± 34.3 0.09
  1. Abbreviations: PTV planning target volume, D 98% dose to 98% of the structure, D 2% dose to 2% of the structure, CN conformation number, V 30 volume (%) of receiving 30 Gy, D mean mean dose, MU monitor unit
  2. Data are shown as mean values with one standard deviation