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Table 5 Univariate and multivariate analysis for Progression Free Survival

From: The prognostic role of hemoglobin levels in patients undergoing concurrent chemo-radiation for anal cancer

 

Univariate Analysis

Multivariate Analysis

Variable

HR (95% CI)

p-value

HR (95%CI)

p-value

Age > 65

1.04 (0.39–1.70)

0.82

NA

NA

Male sex

1.17 (0.44–1.90)

0.52

NA

NA

G3 vs G1

G2 vs G1

1.87 (0.90–3.88)

1.76 (0.51–6.10)

0.92

0.38

NA

NA

NA

NA

T3-T4 vs T1-T2

1.73 (0.89–3.33)

0.11

NA

NA

N + ve vs N -ve

2.16 (1.18–3.96)

0.012

1.98 (1.01–3.88)

0.046

RT total dose

1.12 (0.79–1.58)

0.52

NA

NA

Boost: yes vs no

0.84 (0.32–2.18)

0.72

NA

NA

OTT > 42 days

1.18 (0.53–1.85)

0.38

NA

NA

Hb

0.57 (0.39–0.85)

0.005

0.78 (0.53–1.15)

0.12

Response

5.39 (2.79–10.4)

< 0.0001

5.43 (2.75–10.70)

< 0.0001

  1. RT Radiotherapy, Hb Basal haemoglobin levels (gr/dl), Boost Radiotherapy boost: given vs not, Response Incomplete response vs complete response, OTT Total legth of chemo-radiation treatment, N node, +ve positive, −ve negative, HR hazard ratio, CI confidence interval, NA not available