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Table 6 Predominant symptoms prior to re-irradiation and their relative improvement development during follow-up

From: Evaluation of particle radiotherapy for the re-irradiation of recurrent intracranial meningioma

  Symptoms before particle re-irradiation Symptoms at last follow-up Clinical outcome
Predominant clinical symptoms low grade (CTCAE I-II) high grade (CTCAE III or higher) low grade (CTCAE I-II) high grade (CTCAE III or higher) stable or improvement worsening
n= % n= % n= % n= % n= % n= %
sensory impairment 17 40,5% 1 2,4% 14 33,3% 1 2,4% 16 38,1% 1 2,4%
motor impairment 12 28,6% 3 7,1% 9 21,4% 1 2,4% 13 31,0% 3 7,1%
visual impairment 11 26,2% 6 14,3% 7 16,7% 9 21,4% 12 28,6% 4 9,5%
cognitive impairment 9 21,4% 0 0,0% 5 11,9% 1 2,4% 10 23,8% 0 0,0%
hearing impairment 7 16,7% 3 7,1% 9 21,4% 3 7,1% 10 23,8% 2 4,8%
headaches 6 14,3% 0 0,0% 7 16,7% 0 0,0% 10 23,8% 2 4,8%
seizures 5 11,9% 0 0,0% 4 9,5% 0 0,0% 6 14,3% 1 2,4%
nausea 4 9,5% 0 0,0% 3 7,1% 1 2,4% 8 19,0% 2 4,8%
dizziness 2 4,8% 1 2,4% 3 7,1% 1 2,4% 4 9,5% 2 4,8%
facial pain 2 4,8% 1 2,4% 3 7,1% 1 2,4% 4 9,5% 2 4,8%
fatigue 1 2,4% 0 0,0% 5 11,9% 0 0,0% 9 21,4% 2 4,8%