Table 4 Dose statistics (EQD2) for different organs at risk, regarded independently by tumor location: All locations (n = 41), only skull base tumors (n = 31) and a subgroup of especially complex cases with tumors adjoining to OAR (n = 28)
From: Evaluation of particle radiotherapy for the re-irradiation of recurrent intracranial meningioma
median mean dose | IQR | mean mean dose | std dev | median max dose | IQR | mean max dose | std dev | |
|---|---|---|---|---|---|---|---|---|
All locations, n = 41 | ||||||||
brain stem | 1,1 | 0,1–3,4 | 2,5 | 4,6 | 21,1 | 1–37,5 | 23,1 | 18,1 |
optic chiasm | 3,5 | 0–11,7 | 7,7 | 10,7 | 19,6 | 0,2–35,9 | 20,4 | 19,3 |
left optic nerve | 2,9 | 0–11,3 | 9,8 | 15,6 | 20,3 | 0,1–43,6 | 23,9 | 22,9 |
right optic nerve | 1,7 | 0,1–9 | 10,7 | 18,5 | 16,1 | 0,3–44,3 | 24,0 | 25,3 |
Only skull base, n = 31 | ||||||||
brain stem | 2,0 | 0,9–3,9 | 3,4 | 5,2 | 31,7 | 19,9–40,2 | 31,1 | 13,9 |
optic chiasm | 5,5 | 2,7–16 | 10,3 | 11,5 | 23,7 | 15–41,2 | 27,2 | 17,8 |
left optic nerve | 5,9 | 2,2–21,2 | 13,7 | 17,1 | 29,6 | 17,7–48,7 | 32,9 | 21,1 |
right optic nerve | 4,3 | 0,8–35,7 | 14,9 | 20,5 | 25,7 | 11–54,2 | 32,1 | 24,9 |
Complex cases, n = 28 | ||||||||
brain stem | 2,0 | 0,9–3,8 | 3,4 | 5,2 | 31,7 | 20,2–38,4 | 30,3 | 12,6 |
optic chiasm | 6,0 | 2,9–16,6 | 10,9 | 11,6 | 24,6 | 16,1–40,6 | 28,1 | 17,2 |
left optic nerve | 6,1 | 1,8–23,6 | 14,5 | 17,4 | 29,6 | 18,6–50,1 | 34,0 | 20,9 |
right optic nerve | 2,9 | 0,8–29,4 | 14,1 | 20,1 | 25,7 | 12,8–52,4 | 31,8 | 24,2 |