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Table 1 Patient characteristics univariate analysis

From: Identifying risk factors for L’Hermitte’s sign after IMRT for head and neck cancer

 

Non-LS (n = 75)

LS (n = 42)

Odds Ratio (95% CI)

p-value

Patient characteristics

Mean age ± SD

59.7 ± 8.7

56.6 ± 11.4

0.96 (0.93–1.01)

0.1a

 -Difference (95% CI)

3.1 (− 0.9 to 7)

  

 -Age range

34–79

38–78

  

Male

64 (85%)

33 (79%)

0.63 (0.3–2.2)

0.4b

 -Difference (95% CI)

−6.7% (−21.5 to 8.1)

  

Tumour characteristics

SCC

68 (90.7%)

36 (85.7%)

0.62 (0.3–2.6)

0.2b

 -Oropharynx

43 (57.3%)

26 (61.9%)

 

> 0.9

 -Oral Cavity

9 (12.0%)

2 (4.8%)

 

0.4

 -Larynx

8 (10.6%)

2 (4.8%)

 

0.4

 -CUP

6 (8.0%)

1 (2.4%)

 

0.3

 -Hypopharynx

1 (1.2%)

2 (4.4%)

 

> 0.9

 -Nasopharynx

1 (1.2%)

3 (6.7%)

 

> 0.9

Salivary gland

7 (9.3%)

6 (14.3%)

1.6 (0.4–3.9)

> 0.9

Treatment plan

≥65 Gy prescribed

60 (80.0%)

31 (73.8%)

0.71 (0.4–2.1)

0.7b

Unilateral radiotherapy

20 (26.7%)

18 (42.8%)

2.06 (0.6–3.0)

0.07b

Cisplatin prescribed

39 (52.0%)

26 (61.9%)

1.5 (0.6–2.6)

0.3b

 -Cisplatin received

39 (52.0%)

24 (57.1%)

1.23(0.5–2.3)

0.7b

Cetuximab prescribed

8 (10.7%)

2 (4.8%)

0.42 (0.1–3.4)

0.3b

No chemotherapy

28 (37.3%)

14 (33.3%)

0.84 (0.4–2.1)

0.8b

Neurological Risk Factors

Hypertension

25 (33.3%)

8 (19.0%)

0.47 (0.3–1.79)

0.1b

Diabetes

12 (16.0%)

1 (2.4%)

0.13 (0.1–3.3)

0.03b

  1. Abbreviations: CI – confidence interval, SD – standard deviation, CUP – cancer of unknown primary aStudent’s t test, bFisher’s exact test