Table 1 Dose objectives for each fractionation regimen, based on standard linear-quadratic model biologically effective doses calculated with α/β=3
Structure | Volume (cm3) | 5 fraction | 8 fraction | 15 fraction | |||
|---|---|---|---|---|---|---|---|
DV (Gy) | Dmax (Gy) | DV (Gy) | Dmax (Gy) | DV (Gy) | Dmax (Gy) | ||
Trachea and ipsilateral bronchus | < 4 | 18 (3.6/fx) | 38 (7.6/fx) | 21 (2.6/fx) | 46 (5.8/fx) | 25.5 (1.7/fx) | 58.5 (3.9/fx) |
Spinal cord | < 0.25 | 22.5 (4.5/fx) | 30 (6.0/fx) | 26.5 (3.3/fx) | 36 (4.5/fx) | 32 (2.1/fx) | 45 (3.0/fx) |
Spinal cord | < 1.2 | 13.5 (2.7/fx) | 15.5 (1.9/fx) | 18 (1.2/fx) | |||
Esophagus | < 5 | 27.5 (5.5/fx) | 35 (7.0/fx) | 32.5 (4.1/fx) | 42 (5.3/fx) | 41 (2.7/fx) | 53 (3.5/fx) |
Ipsilateral brachial plexus | < 3 | 30 (6.0/fx) | 32 (6.4/fx) | 36 (4.5/fx) | 38.5 (4.8/fx) | 45 (3.0/fx) | 48 (3.2/fx) |
Heart/pericardium | < 15 | 32 (6.4/fx) | 38 (7.6/fx) | 38.5 (4.8/fx) | 46 (5.8/fx) | 48 (3.2/fx) | 58 (3.9/fx) |
Great vessels | < 10 | 47 (9.4/fx) | 53 (10.6/fx) | 57.5 (7.2/fx) | 65 (8.1/fx) | 74 (4.9/fx) | 84 (5.6/fx) |
Skin | < 10 | 30 (6.0/fx) | 32 (6.4/fx) | 36 (4.5/fx) | 38.5 (4.8/fx) | 45 (3.0/fx) | 48 (3.2/fx) |
Lung (right and left) | 1500 | 12.5 (2.5/fx) | 14 (1.8/fx) | 16.5 (1.1/fx) | |||
Lung (right and left) | 1000 | 13.5 (2.7//fx) | 15.5 (1.9/fx) | 18 (1.2/fx) | |||