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Table 2 Dose constraints for treatment of prostate cancer using volumetric-modulated arc therapy in each institution

From: Evaluation of multiple institutions’ models for knowledge-based planning of volumetric modulated arc therapy (VMAT) for prostate cancer

Institute

Organ

Target

Rectum

Bladder

CTV

PTV

A

Ractal wall

Bladder wall

CTV

PTV

V78 (Gy) ≤ 0.1 cm3

V70 (Gy) ≤ 35%

Dmin ≥100%

D50 = 100%

V70 (Gy) ≤ 25%

V40 (Gy) ≤ 60%

  

V60 (Gy) ≤ 35%

   

V40 (Gy) ≤ 60%

   

B

Ractal wall

Bladder wall

CTV

PTV sub. Rectum

V78 (Gy) < 1%

V70 (Gy) < 35%

 

Dmean < 103%

V70 (Gy) < 20%

V40 (Gy) < 60%

 

Dmin > 99%

V60 (Gy) < 30%

  

Dmax < 110%

V40 (Gy) < 60%

  

D95 = 100%

C

Rectum

Bladder

CTV

PTV

V70 (Gy) ≤ 5%

V80 (Gy) ≤ 5%

D98 ≥ 98%

Dmean = 100%

V65 (Gy) ≤ 10%

V75 (Gy) ≤ 15%

D2 ≤ 105%

D95 ≥ 95%

V60 (Gy) ≤ 20%

V70 (Gy) ≤ 25%

 

V90 ≥ 98%

V40 (Gy) ≤ 40%

V60 (Gy) ≤ 40%

 

D2 ≤ 105%

D

Rectum sub. PTV

Bladder sub. PTV

CTV

PTV sub. (Rectum and bladder)

D50 ≤ 69.7%

D5 ≤ 78.9%

D95 = 100%

68.4% ≤ D5 ≤ 71.1%

D5 ≤ 78.9%

D50 ≤ 72.4%

88.2% ≤ D5 ≤ 92.1%

65.8% ≤ D50 ≤ 71.1%

  

85.5% ≤ D50 ≤ 88.2

64.5% ≤ D95 ≤ 68.4%

  

81.6% ≤ D95 ≤ 85.5

 

E

Ractal wall

Bladder wall

CTV

PTV

V78 (Gy) ≤ 1%

V70 (Gy) ≤ 35%

 

Dmean = 100%

V70 (Gy) ≤ 20%

V40 (Gy) ≤ 60%

 

D95 ≥ 95%

V60 (Gy) ≤ 35%

  

V90 ≥ 98%

V40 (Gy) ≤ 60%

  

Dmax ≤110%

  1. Abbreviations: CTV the clinical target volume, PTV the planning target volume, Dmean mean dose, Dmin minimum dose, Dmax maximum dose, V80, V78, V70, V65, V60, and V40 the OAR volume ratio that receives a dose exceeding 80 Gy, 78 Gy, 70 Gy, 65 Gy, 60 Gy, and 40 Gy, V90 the volume ratio receiving 90% of the prescribed dose, D95, D50, D5, and D2 the dose received by at least 95%, 50%, 5.0%, and 2.0% of the volume