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Table 3 Dosimetric comparison between PBT and 3DCRT, PBT and IMRT

From: Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced esophageal squamous cell carcinoma

End point

DVH parameters

Technique

Mean

SD

SE mean

p value.

(vs. 3DCRT)

p value.

(vs. IMRT)

Lung

V20 (%)

PBT

11.6607

5.18604

.99805

.001

< 0.01

  

3DCRT

16.9652

5.64638

1.08665

  
  

IMRT

17.7941

5.19620

1.00001

  
 

V15 (%)

PBT

17.8696

7.22321

1.39011

.052

.006

  

3DCRT

21.6615

6.75645

1.30028

  
  

IMRT

22.9630

5.64911

1.08717

  
 

V10 (%)

PBT

21.3307

9.07254

1.74601

.058

< 0.01

  

3DCRT

25.7222

7.46624

1.43688

  
  

IMRT

30.0181

6.84990

1.31826

  
 

V5 (%)

PBT

25.2478

10.77897

2.07441

.005

< 0.01

  

3DCRT

33.0893

8.79872

1.69331

  
  

IMRT

45.1811

10.52645

2.02582

  
 

Mean dose (Gy)

PBT

5.8322

2.24148

.43137

< 0.01

< 0.01

  

3DCRT

8.2111

2.14654

.41310

  
  

IMRT

9.4778

2.17052

.41772

  

Heart

V40 (%)

PBT

16.3059

11.42262

2.19828

< 0.01

0.012

  

3DCRT

48.1837

21.03337

4.04787

  
  

IMRT

26.5770

16.91562

3.25541

  
 

V30 (%)

PBT

22.0252

14.45506

2.78188

< 0.01

< 0.01

  

3DCRT

56.1574

21.49217

4.13617

  
  

IMRT

50.7126

23.40755

4.50479

  
 

V20 (%)

PBT

38.4963

23.91227

4.60192

< 0.01

< 0.01

  

3DCRT

64.1178

23.03079

4.43228

  
  

IMRT

69.3259

26.97548

5.19143

  
 

Mean dose (Gy)

PBT

17.6089

9.68207

1.86331

< 0.01

.001

  

3DCRT

30.9844

11.45297

2.20412

  
  

IMRT

9.4778

2.17052

.41772

  

Spinal cord

Maximum dose (Gy)

PBT

38.1400

4.96680

.95586

< 0.01

.155

  

3DCRT

47.2896

2.22998

.42916

  
  

IMRT

39.7119

2.64873

.50975

  

CI

 

PBT

1.8796

.21319

.04103

< 0.01

< 0.01

  

3DCRT

3.1886

.61704

.11875

  
  

IMRT

1.6243

.23493

.04521

  
  1. SD standard deviation, SE standard error, CI conformity index