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Table 2 Cumulative incidence of in-breast recurrences (IBR) and Kaplan-Meier estimates of overall survival (OS)

From: Role of postoperative radiotherapy in reducing ipsilateral recurrence in DCIS: an observational study of 1048 cases

 

IBR

OS

 
 

5 y (%)

10 y (%)

p

5 y (%)

10 y (%)

p

Age at diagnosis (years)

  < 50

12.6

17.6

0.251

100.0

98.5

< 0.001

 50–69

9.7

16.4

 

98.2

95.1

 

  ≥ 70

7.0

13.8

 

88.1

74.6

 

Tumour localisation

 Left

9.4

14.8

0.134

97.0

93.0

0.830

 Right

11.0

18.3

 

97.6

93.8

 

Tumour size

  < 25 mm

12.6

17.5

0.274

96.7

94.9

0.225

  ≥ 25 mm

6.7

6.7

 

88.9

84.2

 

Grade

 G1

12.0

22.4

0.212

93.3

93.3

0.444

 G2

5.3

12.4

 

96.6

95.3

 

 G3

11.7

15.9

 

99.4

90.7

 

Multifocality

 no

10.0

16.2

0.592

97.3

93.4

0.972

 yes

11.1

19.4

 

97.6

93.1

 

Resection margins

 R0

9.3

15.6

0.526

97.6

93.1

0.953

 R1–2

14.8

20.2

 

96.2

96.2

 

Hormone receptor status

 positive

8.6

16.2

0.719

97.2

94.3

0.501

 negative

13.0

15.6

 

97.6

90.1

 

Radiotherapy

 no

13.2

20.0

0.012

95.1

90.0

0.001

 yes

8.0

13.6

 

99.1

96.7

 

Endocrine therapy

 no

10.9

17.4

0.111

97.2

93.6

0.319

 yes

5.5

10.7

 

97.6

92.3