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Table 1 Cohort characteristics of the different treatment groups. BCS: breast conserving surgery

From: Role of postoperative radiotherapy in reducing ipsilateral recurrence in DCIS: an observational study of 1048 cases

  BCS BCS + Radiotherapy
  388 patients 660 patients
  n (%)a n (%)a p-value
Age at diagnosis (years)
  < 50 96 (24.7) 150 (22.7) < 0.001
 50–69 224 (57.8) 448 (67.9)  
  ≥ 70 68 (17.5) 62 (9.4)  
 median age (years) 58.8   57.3   
Tumor side
 Left 217 (56.5) 354 (53.6) 0.368
 Right 167 (43.5) 306 (46.4)  
unknown [4] [1.0]    
Tumour stage
 pTis 388 (100) 660 (100)  
Tumour size
  < 25 mm 26 (74.3) 41 (66.1) 0.404
  ≥ 25 mm 9 (25.7) 21 (33.9)  
unknown [353] [90.9] [598] [90.6]  
Nodal status
 pN0 45 (11.6) 139 (21.1) < 0.001
 pN1 0 (0.0) 2 (0.3)  
 pNx/unknown 343 (88.4) 519 (78.6)  
Grade
 G1 44 (29.9) 63 (13.3) < 0.001
 G2 60 (40.8) 175 (36.8)  
 G3 43 (29.3) 237 (49.9)  
unknown [241] [62.1] [185] [28.0]  
Multifocality
 no 365 (94.1) 633 (95.9) 0.178
 yes 23 (5.9) 27 (4.1)  
Resection margins
 R0 235 (97.1) 554 (96.5) 0.666
 R1–2 7 (2.9) 20 (3.5)  
Rx/unknown [146] [37.6] [86] [13.0]  
Hormone Receptor
 positive 215 (89.6) 492 (82.7) 0.012
 negative 25 (10.4) 103 (17.3)  
unknown [148] [38.1] [65] [9.8]  
Endocrine therapy
 no 355 (91.5) 542 (82.1) < 0.001
 yes 33 (8.5) 118 (17.9)  
  1. aPercentages of the presented subcategories are related to the sum of each item with available data; missing values are not taken into account