Table 1 Cohort characteristics of the different treatment groups. BCS: breast conserving surgery
BCS | BCS + Radiotherapy | ||||
|---|---|---|---|---|---|
388 patients | 660 patients | ||||
n | (%)a | n | (%)a | p-value | |
Age at diagnosis (years) | |||||
< 50 | 96 | (24.7) | 150 | (22.7) | < 0.001 |
50–69 | 224 | (57.8) | 448 | (67.9) | |
≥ 70 | 68 | (17.5) | 62 | (9.4) | |
median age (years) | 58.8 | 57.3 | |||
Tumor side | |||||
Left | 217 | (56.5) | 354 | (53.6) | 0.368 |
Right | 167 | (43.5) | 306 | (46.4) | |
unknown | [4] | [1.0] | |||
Tumour stage | |||||
pTis | 388 | (100) | 660 | (100) | |
Tumour size | |||||
< 25 mm | 26 | (74.3) | 41 | (66.1) | 0.404 |
≥ 25 mm | 9 | (25.7) | 21 | (33.9) | |
unknown | [353] | [90.9] | [598] | [90.6] | |
Nodal status | |||||
pN0 | 45 | (11.6) | 139 | (21.1) | < 0.001 |
pN1 | 0 | (0.0) | 2 | (0.3) | |
pNx/unknown | 343 | (88.4) | 519 | (78.6) | |
Grade | |||||
G1 | 44 | (29.9) | 63 | (13.3) | < 0.001 |
G2 | 60 | (40.8) | 175 | (36.8) | |
G3 | 43 | (29.3) | 237 | (49.9) | |
unknown | [241] | [62.1] | [185] | [28.0] | |
Multifocality | |||||
no | 365 | (94.1) | 633 | (95.9) | 0.178 |
yes | 23 | (5.9) | 27 | (4.1) | |
Resection margins | |||||
R0 | 235 | (97.1) | 554 | (96.5) | 0.666 |
R1–2 | 7 | (2.9) | 20 | (3.5) | |
Rx/unknown | [146] | [37.6] | [86] | [13.0] | |
Hormone Receptor | |||||
positive | 215 | (89.6) | 492 | (82.7) | 0.012 |
negative | 25 | (10.4) | 103 | (17.3) | |
unknown | [148] | [38.1] | [65] | [9.8] | |
Endocrine therapy | |||||
no | 355 | (91.5) | 542 | (82.1) | < 0.001 |
yes | 33 | (8.5) | 118 | (17.9) | |