From: From IB2 to IIIB locally advanced cervical cancers: report of a ten-year experience
Characteristics | Whole set of patients (n = 94) | Complete CCRT (n = 41) | Incomplete CCRT (n = 53) | p-value |
---|---|---|---|---|
Age, years, median (IQR) | 63.0 (51.3–75.0) | 59.1 (50.7–73.4) | 65.3 (54.4–76.0) | NS |
PS, n (%) | ||||
PS ≤ 1 | 83 (88.3) | 24 (58.5) | 20 (37.7) | 0.03a |
PS ≥ 2 | 10 (10.6) | 16 (39.0) | 33 (62.3) | |
UK | 1 (1.1) | 1 (2.4) | 0 (0) | |
Charlson combined age-comorbidity index, n (%) | ||||
0 | 9 (9.6) | 4 (9.8) | 5 (9.4) | NS |
1–2 | 29 (30.9) | 16 (39.0) | 13 (24.5) | |
3–4 | 31 (33.0) | 13 (31.7) | 18 (34.0) | |
≥ 5 | 25 (26.6) | 8 (19.5) | 17 (32.1) | |
Quintile EDI | ||||
1 | 8 (8.5) | 4 (9.8) | 4 (7.5) | NS |
2 | 15 (16.0) | 8 (19.5) | 7 (13.2) | |
3 | 11 (11.7) | 2 (4.9) | 9 (17.0) | |
4 | 24 (25.5) | 14 (34.1) | 10 (18.9) | |
5 | 29 (30.9) | 11 (26.8) | 18 (34.0) | |
UK | 7 (7.4) | 2 (4.9) | 5 (9.4) | |
Histological type, n (%) | ||||
Squamous cell carcinoma | 72 (76.6) | 33 (80.5) | 39 (73.6) | NS |
Adenocarcinoma | 14 (14.9) | 6 (14.6) | 8 (15.1) | |
Other | 8 (8.6) | 2 (4.9) | 6 (11.3) | |
Differentiation grade, n (%) | ||||
High | 24 (25.5) | 12 (29.3) | 12 (22.6) | NS |
Moderate | 26 (27.7) | 12 (29.3) | 14 (26.4) | |
Low | 32 (34.0) | 12 (29.3) | 20 (37.7) | |
UK | 12 (12.8) | 5 (12.2) | 7 (13.2) | |
FIGO Stage, n (%) | ||||
IB2 | 10 (10.6) | 5 (12.2) | 5 (9.4) | NS |
IIA | 21 (22.3) | 15 (36.6) | 16 (30.2) | |
IIB | 48 (51.0) | 19 (46.3) | 29 (54.7) | |
IIIA | 4 (4.3) | 0 (0) | 4 (7.5) | |
IIIB | 11 (11.7) | 7 (17.1) | 4 (7.5) | |
Largest MRI tumour diameter, n (%) | ||||
< 4 cm | 28 (29.8) | 13 (31.7) | 15 (28.3) | NS |
4 to 6 cm | 27 (27.7) | 12 (29.3) | 14 (26.4) | |
> 6 cm | 15 (22.3) | 4 (9.8) | 11 (20.8) | |
UK | 24 (25.5) | 10 (24.4) | 14 (26.4) | |
Lymph node involvement according to initial workup, n (%) | ||||
Pelvic | 32 (34.0) | 13 (31.7) | 19 (35.8) | NS |
Para-aortic | 0 (0) | 0 (0) | (0) | |
Initial workup, n (%) | ||||
Pelvic MRI | 87 (92.6) | 40 (97.6) | 47 (94.0) | NS |
Cystoscopy | 33 (35.1) | 15 (37.5) | 18 (36.7) | NS |
PET-CT | 31 (33.0) | 11 (28.9) | 20 (40.0) | NS |
Initial haemoglobin, g/dL, median (IQR) | 12.9 (11.9–14.2) | 13.1 (12.3–14.2) | 12.8 (11.5–13.9) | NS |