Table 2 Summary of the best estimates and 95% confidence intervals of the parameters of the three examined normal tissue complication probability models for four acute bladder symptoms, respectively
Lyman-Kutcher-Burman (LKB) model | ||||
Symptom | Vref | D50 (Gy) | m | n |
 Urinary urgency | Whole | 64.2 (54.6–78.7) | 0.50 (0.35–0.88) | 1.00 (0.40–7.00) |
 Urinary incontinence | Whole | 95.0 (77.2–130.6) | 0.45 (0.35–0.62) | 0.50 (0.13–3.51) |
 Frequency | 150cm3 | 83.1 (61.3–132.9) | 0.56 (0.43–0.81) | 1.00 (0.55–7.00) |
 Nocturia | 150cm3 | 85.4 (63.0–143.1) | 0.60 (0.47–0.87) | 1.00 (0.40–7.00) |
Logit model | ||||
Symptom | Vref | D50 (Gy) | k | n |
 Urinary urgency | Whole | 67.6 (60.0–77.7) | 3.04 (1.67–4.63) | 0.49 (0.20–3.44) |
 Urinary incontinence | Whole | 96.7 (85.8–107.6) | 4.55 (3.19–5.92) | 0.01 (0.01–0.07) |
 Frequency | 150cm3 | 117.2 (82.0–183.1) | 1.35 (0.95–1.86) | 1.00 (0.40–7.00) |
 Nocturia | 150cm3 | 123.1 (81.6–197.0) | 1.23 (0.86–1.69) | 1.00 (0.40–7.00) |
Relative Seriality model | ||||
Symptom | Vref | D50 (Gy) | γ | s |
 Urinary urgency | Whole | 68.5 (55.6–86.4) | 0.51 (0.28–0.74) | 10−4 (10−5-7 × 10−4) |
 Urinary incontinence | Whole | 103.1 (83.8–138.0) | 0.59 (0.41–0.81) | 0.85 (0.08–5.92) |
 Frequency | 150cm3 | 134.7 (84.2–336.7) | 0.33 (0.18–0.48) | 0.82 (0.33–5.73) |
 Nocturia | 150cm3 | 119.5 (74.7–280.9) | 0.34 (0.18–0.49) | 0.73 (0.29–5.12) |