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Table 4 Factors associated with treatment-related esophageal stricture

From: Additional radiotherapy following endoscopic submucosal dissection for T1a-MM/T1b-SM esophageal squamous cell carcinoma improves locoregional control

Factors

 

Esophageal stricture

(n = 4)

No esophageal stricture

(n = 23)

p-Value

Age (years; mean ± SD)

 

65 ± 6.5

67 ± 1.4

0.61

Gender

Male

2

20

0.14

Female

2

3

 

Number of primary tumors

Single

1

21

0.013*

Multiple

3

2

 

Invasion depth

pT1a-MM

3

13

0.62

pT1b-SM1

1

10

 

Circumferential extent of ESD

< 3/4

0

17

0.012*

≥3/4

4

6

 

Longitudinal diameter of ESD (mm; mean ± SD)

 

72 ± 14

38 ± 14

0.0033*

Additional chemotherapy

(+)

1

7

1.00

(−)

3

16

 

Additional RT

(+)

2

11

1.00

(−)

2

12

 
  1. ESD Endoscopic submucosal dissection, RT Radiotherapy, pT1a-MM Tumor invading muscularis mucosae, pT1b-SM1 Tumor invading submucosa less than 200 μm below the MM. *p < 0.05