Additional radiotherapy following endoscopic submucosal dissection for T1a-MM/T1b-SM esophageal squamous cell carcinoma improves locoregional control

Table 3 Patients with treatment-related esophageal strictures (n = 4)

Additional RT	Toxicity grade	Invasion depth	Circumference of ESD^a	Longitudinal diameter of ESD (mm)	Treatment of strictures	Outcome of strictures
(+)	Grade 2	pT1a-MM	5/6	68	EBD	Improved
(+)	Grade 3	pT1b-SM1	Complete	75	EBD, stent	Remained
(−)	Grade 2	pT1a-MM	3/4	55	EBD	Improved
(−)	Grade 3	pT1a-MM	Complete	90	EBD	Remained

^aNo patients with mucosal defects involving less than 3/4 of the circumference after ESD developed treatment-related strictures
RT radiotherapy, ESD endoscopic submucosal dissection, T1a-MM tumor invading muscularis mucosae, T1b-SM1 tumor invading the upper third of the submucosa, EBD endoscopic balloon dilatation

ISSN: 1748-717X