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Table 1 Total beam-on time (BOT), mean liver dose (MLD) and proportion of circulating lymphocytes receiving ≥0.5Gy (CL0.5) by treatment modality, beam energy and dose rate as a mean for all intrahepatic locations

From: Modelling the immunosuppressive effect of liver SBRT by simulating the dose to circulating lymphocytes: an in-silico planning study

1. Treatment modalities and mean MLD and CL0.5 of all locations

Treatment modality

Beam energy

Flattening filter

Dose rate (MU/min)

Fields / Arcs

Total BOT

MLD

CL0.5

3DCRT

10 MV

FFF

2400

7

57 s

4.3 Gy

15.9%

3DCRT

6 MV

FFF

1400

7

111 s

4.3 Gy

23.6%

3DCRT

6 MV

FF

600

7

253 s

4.3 Gy

30.9%

VMAT

10 MV

FFF

2400

2

74 s

3.6 Gy

19.0%

VMAT

6 MV

FFF

1400

3

147 s

3.6 Gy

23.6%

VMAT

6 MV

FF

600

4

363 s

3.6 Gy

25.1%