Table 3 Dosimetric parameters for brain tissue for conventional volumetric modulated arc therapy (C-VMAT) and HyperArc VMAT (HA-VMAT) plans
Dosimetric parameter | All (n = 23) | Single-isocentric C-VMAT cases (n = 15) | Multi-isocentric C-VMAT cases (n = 8) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-VMAT | HA-VMAT | p-value | C-VMAT | HA-VMAT | p-value | C-VMAT | HA-VMAT | p-value | |||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||
V16Gy | 5.3 | 3.8 | 3.8 | 2.8 | <0.01 | 4.7 | 2.6 | 3.3 | 1.9 | 0.01 | 6.4 | 5.5 | 4.5 | 4.1 | 0.01 |
V14Gy | 7.7 | 5.7 | 5.5 | 3.9 | <0.01 | 6.8 | 3.9 | 4.8 | 2.7 | 0.01 | 9.5 | 8.1 | 6.7 | 5.6 | 0.01 |
V12Gy | 11.3 | 8.4 | 7.9 | 5.6 | <0.01 | 10.0 | 5.9 | 6.9 | 3.9 | 0.01 | 13.8 | 11.9 | 9.7 | 7.8 | 0.01 |
V10Gy | 17.1 | 12.8 | 11.6 | 8.0 | <0.01 | 15.3 | 9.5 | 10.2 | 5.8 | 0.01 | 20.5 | 17.7 | 14.3 | 11.2 | 0.01 |
V8Gy | 27.0 | 20.6 | 17.9 | 12.4 | <0.01 | 24.4 | 15.9 | 15.8 | 9.0 | 0.01 | 32.1 | 27.9 | 22.0 | 17.1 | 0.01 |
V6Gy | 45.5 | 33.8 | 29.5 | 21.1 | <0.01 | 41.0 | 28.0 | 25.5 | 14.6 | 0.01 | 53.8 | 43.7 | 37.0 | 29.5 | 0.01 |
V4Gy | 86.9 | 62.3 | 58.1 | 48.0 | <0.01 | 78.1 | 55.7 | 47.7 | 28.6 | 0.01 | 103.3 | 74.2 | 77.4 | 70.4 | 0.01 |
V2Gy | 205.1 | 123.7 | 196.4 | 166.7 | 0.09 | 185.8 | 118.7 | 143.0 | 93.5 | <0.01 | 241.2 | 132.8 | 296.4 | 228.7 | 0.09 |