Fig. 4

Example cases of anatomical changes during the treatment course for different entities. PTVs are shown in the initial CT (dashed lines, left side) and adapted PTVs in the repeated CT (solid lines, right side): a Head and neck case of tongue cancer (left) with tumor progress (right). The PTVs receiving 56,1 Gy and 66 Gy are highlighted in red and orange, respectively. b Head and neck case and CUP syndrome (left) with volume change due to edema reduction (right). PTVs receiving 59,4 Gy and 66 Gy contours are highlighted in red and orange, respectively. c Thorax case with lung cancer (left) and a growing pleural effusion (right). PTV receiving 50,4 Gy and 61,6 Gy are highlighted in red and blue, respectively. d Thorax case with lung cancer (left) and a mediastinal shift (right). PTVs receiving 50,4 Gy and 61,6 Gy are highlighted in red and blue, respectively. e Pelvis case with prostate cancer (left) and change in rectal volume (right). PTVs receiving 45,9 Gy and 56,7 Gy are highlighted in red and orange, respectively. f Pelvis case with prostate cancer and irradiation of bone and lymphatic metastasis (left) and decrease in lymph node size (right). PTVs receiving 40 Gy and 50 Gy are highlighted in red and orange, respectively