Table 3 Effect of ATMi and DNAPKi for photon irradiation of A549 cells at indicated doses

Photons

0 nM

100 nM ATMi

p-value

Ratio

0 nM

100 nM ATMi

p- value

Ratio

SF_4Gy

0.43 ± 0.07

0.29 ± 0.10

0.12

1.48 ± 0.25

0.59 ± 0.02

0.37 ± 0.07

0.007

1.57 ± 0.23

SF_8Gy

0.11 ± 0.04

0.05 ± 0.01

0.06

2.11 ± 0.31

0.27 ± 0.03

0.12 ± 0.02

0.002

2.30 ± 0.26

100 nM DNAPKi

100 nM DNAPKi

SF_4Gy

0.29 ± 0.07

0.12

1.51 ± 0.09

0.18 ± 0.01

<0.0001

3.34 ± 0.04

SF_8Gy

0.07 ± 0.03

0.072

1.59 ± 0.14

0.07 ± 0.03

0.0002

9.03 ± 3.83