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Fig. 2 | Radiation Oncology

Fig. 2

From: Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation

Fig. 2

Lack of cytotoxicity of utilized ATMi and DNAPKi alone at pharmacologically relevant doses. PE of A549 cells after treatment with dose series of ATMi (light grey) or DNAPKi (dark grey), respectively, under normoxia (a) and hypoxia (b). Statistically significant reduction of PE was only found under normoxia for doses ≥1000 nM. Bars represent mean ± SD of three independent experiments with n:4 technical replicates each

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Radiation Oncology

ISSN: 1748-717X

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