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Table 3 Univariate log-rank analysis of IMRT timing, surgical margin status, chemotherapy, histology, and tumor grade on OS, LC and DM

From: Intensity modulated radiation therapy and surgery for Management of Retroperitoneal Sarcomas: a single-institution experience

 

3-year rate (%)

5-year rate (%)

p value

Overall Survival

 Radiation therapy

  Pre-operative RT

80

54

0.85

  Post-operative RT

62

48

 

 Surgical Margins

  Negative (R0)

92

78

0.09

  Positive (R1)

52

35

 

 Chemotherapy

  Yes

67

53

0.74

  No

69

48

 

 Histology

  LMS

77

58

0.48

  Liposarcoma

67

50

 

  Other

60

45

 

 Grade

  Low

86

57

0.58

  High

65

50

 

Local Control

 Radiation therapy

  Pre-operative RT

100

100

0.10

  Post-operative RT

77

69

 

 Surgical Margins

  Negative (R0)

100

100

0.02

  Positive (R1)

79

60

 

 Chemotherapy

  Yes

65

65

0.16

  No

94

85

 

 Histology

  LMS

100

100

0.06

  Liposarcoma

100

75

 

  Other

58

58

 

 Grade

  Low

100

100

0.09

  High

77

68

 

Distant Metastasis

 Radiation therapy

  Pre-operative RT

32

55

0.91

  Post-operative RT

38

45

 

 Surgical Margins

  Negative (R0)

25

34

0.16

  Positive (R1)

27

45

 

 Chemotherapy

  Yes

55

55

0.69

  No

26

44

 

 Histology

  LMS

50

50

0.53

  Liposarcoma

11

33

 

  Other

40

55

 

 Grade

  Low

25

40

0.54

  High

40

49