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Fig. 4 | Radiation Oncology

Fig. 4

From: Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas

Fig. 4

Exemplarily T1-weighted axial MR-images measured 6 min after contrast agent injection. HI-tumors were either treated (upper tumor in each image) or untreated (lower tumors). Tumors were measured before RT (Day 0) and at 4 time points after single doses. Due to the fast growth of untreated tumors, a longer follow-up was not possible. In (a) 37 Gy isodoses of photons and 12C-ions are compared whereas in (b) isoeffective doses with respect to local control at 300 days are shown (18 Gy 12C-ions vs. 37 Gy photons and 37 Gy 12C-ions vs. 75 Gy photons, respectively). A volume increase was seen only in untreated tumors. The light contrast showed edema, whereas dark volumes are a sign for necrotic areas

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