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Table 3 Hematologic toxicities

From: Comparison of neoadjuvant chemoradiation with carboplatin/ paclitaxel or cisplatin/ 5-fluoruracil in patients with squamous cell carcinoma of the esophagus

Hematologic toxicities Intention to treat Per protocol
Carb/TAX n = 20 CDDP/5FU n = 31 p-value Carb/TAX n = 18 CDDP/5FU n = 26 p-value
 ≥ III° 4 (20%) 18 (58%) 0.010 3 (17%) 15 (58%) 0.012
Leukopenia    0.065    0.048
 0° 2 (10%) 3 (10%)   2 (11%) 2 (8%)  
 I° 4 (20%) 4 (13%)   3 (17%) 4 (15%)  
 II° 10 (50%) 6 (19%)   10 (56%) 5 (19%)  
 III° 4 (20%) 15 (48%)   3 (17%) 13 (50%)  
 IV° 0 (0%) 3 (10%)   0 (0%) 2 (8%)  
Thrombocytopenia    0.654    0.364
 0° 15 (75%) 18 (58%)   14 (78%) 14 (54%)  
 I° 2 (10%) 6 (19%)   2 (11%) 6 (23%)  
 II° 2 (10%) 2 (6%)   2 (11%) 2 (8%)  
 III° 1 (5%) 4 (13%)   0 (0%) 3 (12%)  
 IV° 0 (0%) 1 (3%)   0 (0%) 1 (4%)  
Anemia    0.184    0.479
 0° 3 (15%) 0 (0%)   2 (11%) 0 (0%)  
 I° 10 (50%) 19 (61%)   10 (56%) 16 (62%)  
 II° 6 (30%) 9 (29%)   5 (28%) 7 (27%)  
 III° 1 (5%) 3 (10%)   1 (6%) 3 (12%)  
  1. Bold numbers indicate statistical significance with p <0.05