Table 3 Hematologic toxicities
Hematologic toxicities | Intention to treat | Per protocol | ||||
|---|---|---|---|---|---|---|
Carb/TAX n = 20 | CDDP/5FU n = 31 | p-value | Carb/TAX n = 18 | CDDP/5FU n = 26 | p-value | |
≥ III° | 4 (20%) | 18 (58%) | 0.010 | 3 (17%) | 15 (58%) | 0.012 |
Leukopenia | 0.065 | 0.048 | ||||
0° | 2 (10%) | 3 (10%) | 2 (11%) | 2 (8%) | ||
I° | 4 (20%) | 4 (13%) | 3 (17%) | 4 (15%) | ||
II° | 10 (50%) | 6 (19%) | 10 (56%) | 5 (19%) | ||
III° | 4 (20%) | 15 (48%) | 3 (17%) | 13 (50%) | ||
IV° | 0 (0%) | 3 (10%) | 0 (0%) | 2 (8%) | ||
Thrombocytopenia | 0.654 | 0.364 | ||||
0° | 15 (75%) | 18 (58%) | 14 (78%) | 14 (54%) | ||
I° | 2 (10%) | 6 (19%) | 2 (11%) | 6 (23%) | ||
II° | 2 (10%) | 2 (6%) | 2 (11%) | 2 (8%) | ||
III° | 1 (5%) | 4 (13%) | 0 (0%) | 3 (12%) | ||
IV° | 0 (0%) | 1 (3%) | 0 (0%) | 1 (4%) | ||
Anemia | 0.184 | 0.479 | ||||
0° | 3 (15%) | 0 (0%) | 2 (11%) | 0 (0%) | ||
I° | 10 (50%) | 19 (61%) | 10 (56%) | 16 (62%) | ||
II° | 6 (30%) | 9 (29%) | 5 (28%) | 7 (27%) | ||
III° | 1 (5%) | 3 (10%) | 1 (6%) | 3 (12%) | ||