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Table 3 Univariate analysis of prognostic factors

From: Benefit of salvage total pharyngolaryngoesophagectomy for recurrent locally advanced head and neck cancer after radiotherapy

Characteristics

n

2-year overall

survival rate

P-value

Age in years

  

0.285

  > 60

30

42.2%

 

  ≤ 60

36

33.9%

 

Primary

  

0.218

 Larynx

19

22.3%

 

 Hypo-pharynx

40

42.1%

 

 Cervicalesophagus

7

57.1%

 

Previous treatment

  

0.692

 1 course without surgery

30

30.9%

 

 1 course with surgery

26

43.0%

 

 Multiple courses

10

46.7%

 

Time interval between radiation and salvage surgery

  

0.065

  ≤ 6

14

11.3%

 

  > 6

52

41.6%

 

Previous chemo- or targeted therapy

  

0.579

 No

46

40.3%

 

 Yes

20

31.4%

 

Skin invasion

  

0.135

 No

52

41.9%

 

 Yes

14

19.8%

 

Pre-op suspicious carotid artery invasiona

  

0.009

 No

53

42.8%

 

 Yes

13

8.5%

 

Intra-op carotid artery invasionb

  

0.000

 No

40

54.3%

 

 Yes

26

6.2%

 

Pre-op suspicious prevertebral invasiona

  

0.001

 No

55

46.0%

 

 Yes

11

0

 

Intra-op prevertebral invasionb

  

0.327

 No

39

44.1

 

 Yes

27

24.4

 

Pre-op positive cervical nodes

  

0.834

 No

48

38.4%

 

 Yes

18

34.4%

 
  1. aPre-operative suspicious was judged by preoperative CT scan
  2. bintra-op carotid artery invasion was judged by intraoperative detection