Table 1 Dose volume histogram, monitor units and treatment time for hippocampus sparing whole brain irradiation
HS WBRT | |||||
|---|---|---|---|---|---|
Krayenbuehl et al. Mean (range) | RTOG 0933 recommendation | Gondi et al. Mean (range) | Nevelsky et al. Mean (range) | Wang et al. Mean (range) | |
PTV D98% (Gy) | 25.8 (25.0–27.1) | ≥ 25Gy | N/A | 25.7 (25.4–25.9) | |
PTV V95% (%) | 96.4 (95.2–97.8) | N/A | 96.9 (96.1–97.5) | N/A | 96.9 (96.0–97.5) |
PTV D2 (Gy) | 33.5 (32.8–34.6) | ≤37.5 | N/A | 37.2 (36.9–37.6) | 35.1 (34.8–35.6) |
PTV Dmax (Gy) | 36 (35.1–36.5) | N/A | N/A | N/A | N/A |
PTV V30Gy (%) | 92 (92.0–92.0) | = 90 | N/A | 92.1 (90.5–93.2) | N/A |
PTV HI | 0.24 (0.21–0.26) | N/A | 0.3 (0.26–0.34) | 0.36 (0.34–0.37) | 0.26 (0.23–0.33) |
PTV Dmean (Gy) | 31.5 (30.9–32.2) | N/A | N/A | N/A | N/A |
HC D100% (Gy) | 8.1 (7.8–8.5) | ≤ 9 | N/A | 8.4 (7.7–8.9) | 9.3 (8.3–10.0) |
HC Dmean (Gy2) | 7.3 (6.0–7.9) | N/A | 7.3 (7.2–7.6) | N/A | N/A |
HC Dmax (Gy) | 14.1 (12.0–15.3) | ≤ 16 | 15.3 (14.3–15.9) | 14.3 (13.5–15.4) | 16 (14.6–16.9) |
Lens Dmax (Gy) | 4.6 (3.7–5.6) | N/A | 3.8 (3.1–4.3) | N/A | 5.8 (4.5–6.5) |
Opt chiasm Dmax (Gy) | 32.9 (31.7–35.1) | ≤ 37.5 | N/A | 36.2 (33.9–37.2) | 34.7 (33.1–36.8) |
Opt nerve Dmax (Gy) | 33.1 (32.5–33.8) | ≤ 37.5 | N/A | 32.5 (28.3–35.7) | 32.0 (23.7–36.1) |
Lacrymal glands Dmax (Gy) | 10.8 (6.6–15.5) | ≤ 37.5 | N/A | N/A | N/A |
MU | 1481 (1345–1550) | N/A | N/A | 1724 (1622–1914) | N/A |
Effective working time (min) | 4.5 (4.1–5.3) | N/A | N/A | N/A | N/A |