Table 3 Treatment-related adverse events
24 Gy | 30 Gy | 36 Gy | ALL | |
|---|---|---|---|---|
n = 4 | n = 1 | n = 8 | n = 13 | |
Laboratory abnormalities, any grade | ||||
Anemia | 1 | 0 | 2 | 3 |
Leucopenia | 1 | 0 | 2 | 3 |
thrombocytopenia | 2 | 0 | 7 | 9 |
Lymphocytopenia | 3 | 1 | 4 | 8 |
Hypoglycemia | 2 | 1 | 4 | 7 |
Increased alanine aminotransferase | 4 | 1 | 4 | 9 |
Increased aspartate aminotransferase | 3 | 1 | 4 | 8 |
Increased alkaline phosphatase | 2 | 1 | 1 | 4 |
Increased creatinine | 0 | 1 | 3 | 4 |
Hypothyroidism | 1 | 0 | 4 | 5 |
Hyperkalemia | 3 | 1 | 1 | 5 |
Adverse events, any grade | ||||
Fatigue | 4 | 1 | 6 | 11 |
Insomnia | 3 | 0 | 1 | 4 |
Anorexia | 0 | 0 | 3 | 3 |
Weight loss | 0 | 0 | 4 | 4 |
Dysgeusia | 1 | 0 | 8 | 9 |
Dry mouth | 1 | 1 | 2 | 4 |
Nausea | 1 | 0 | 4 | 5 |
Vomiting | 1 | 0 | 3 | 4 |
Dyspnea | 1 | 0 | 6 | 7 |
Hypertension | 3 | 1 | 5 | 9 |
Peripheral edema | 2 | 0 | 1 | 3 |
Dry skin | 1 | 0 | 2 | 3 |
Changes in hair color | 0 | 1 | 2 | 3 |
Hand foot syndrome | 1 | 0 | 2 | 3 |
Laboratory abnormalities, grade 3–4 | ||||
Hypoglycemia | 0 | 0 | 1 | 1 |
Increased alanine aminotransferase | 0 | 0 | 1 | 1 |
Increased aspartate aminotransferase | 0 | 0 | 1 | 1 |
Adverse events, grade 3–4 | ||||
Hypertension | 1 | 0 | 2 | 3 |