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Table 4 Summary of trials with general and local complication rates after spine surgery with and without previous RT

From: Risk for surgical complications after previous stereotactic body radiotherapy of the spine

Study, year

Main type of surgery

Complications rate

Wound complications

Perioperative deaths = 30 days mortality

Overall / Number of patients

RT + S / number of patients

S alone / number of patients

overall / number of surgeries

RT + S / number of surgeries

S alone / number of surgeries

Demura, 2009 [41]

Debulking / stabilization

–

–

–

7.1% / 113

31.8% / 22

1.1% / 91

–

Ghogawala, 2001 [43]

Posterolateral decompression and stabilization

/ 85

–

–

–

32% / 28

12% / 34

–

Lau, 2013 [34]

–

21.7% / 106

23.5% / 81

16% / 25

3.8%/106

–

–

1 (0.9%)

Pascal, 1998 [25]

Post + ant. approach

18.6% / 145

–

–

11% / 145

12%

1%

3 (2%)

Quan, 2011 [21]

Post + ant. approach

26% / 118

42% / 19

–

6.8% / 118

15.8% / 19

5% / 99

9 (7.6%)

Shehadi, 2007 [37]

–

–

–

39% / 87

–

No significant difference

–

Sundaresan, 2002 [42]

Ant. Approach + post. stab.

80

15% / 40

40% / 40

13.8% / 80

25% / 40

2.5% / 40

1 (1.3%)

Wang, 2004 [38]

Posterior approach

14.3% / 140

84

56

11.4% / 140

No significant difference

6 (4.3%)

Wise, 1999 [26]

Post + ant. approach

25% / 80

15.5% / 41

9.3% /39

17.1% / 80

–

–

2 (2.3%)

Yokogawa, 2014 [35]

Total en bloc spondylectomy

40% / 50

77.8% / 18

18.8% / 32

8% / 50

22.2% / 18

0% / 32

–