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Table 2 Univariate analysis of factors affecting biochemical free survival

From: Nadir PSA is a strong predictor of treatment outcome in intermediate and high risk localized prostate cancer patients treated by definitive external beam radiotherapy and androgen deprivation

Factor

HR (95% CI)

p-value

GS

1.299 (1.009–1.672)

0.042

 < 8

1 (reference)

 8–10

2.007 (1.129–3.569)

0.018

bPSA (ng/ml)

1.009 (1.001–1.017)

0.024

 ≤ 20 ng/ml

1 (reference)

 > 20 ng/ml

1.767 (0.970–3.218)

0.063

T-stage

2.226 (1.410–3.515)

0.001

 T1-T2

1 (reference)

 T3-T4

3.079 (1.691–5.608)

<0.001

nPSA (ng/ml)

2.667 (1.79–3.973)

<0.001

 < 0.06

1 (reference)

 ≥ 0.06

3.887 (1.988–7.599)

<0.001

RT dose (Gy)

0.837 (0.703–0.996)

0.045

PSA pre-RT (ng/ml)

1.056 (1.0–1.114)

0.048

ADT duration (months)

0.996 (0.970–1.023)

0.784

Age (years)

0.968 (0.926–1.012)

0.148

Time to Nadir (months)

0.999 (0.969–1.031)

0.965