Skip to main content

Table 3 Univariate and multivariate analyses on prognostic factors of cause-specific survival in patients with stage III disease (n = 239)

From: Preoperative radiotherapy improves survival in rectal signet-ring cell carcinoma-a population-based study

Characteristic

Univariate analysis

Multivariate analysis

 

HR (95% CI)

p

HR (95% CI)

p

Sex

 Male

1

 

 

 Female

1.257 (0.890–1.776)

0.195

Age

1.013 (1.003–1.024)

0.012

1.013 (1.000–1.025)

0.045

Race

 White

1

 

 

 Black

1.463 (0.804–2.665)

0.213

 Other and unknown

1.037 (0.649–1.659)

0.879

Tumor grade

 G1–2

1

 

 

 G3–4

0.616 (0.332–1.143)

0.125

Tumor size (mm)

1.017 (1.010–1.025)

<0.001

1.019 (1.012–1.027)

<0.001

Number of RLNs

0.996 (0.983–1.010)

0.608

Number of PLNs

1.041 (1.018–1.064)

0.001

1.016 (0.990–1.043)

0.222

Treatment

 Surgery alone

1

 

1

 

 Preoperative RT

0.418 (0.262–0.667)

<0.001

0.467 (0.274–0.794)

0.005

 Postoperative RT

0.565 (0.358–0.892)

0.014

0.615 (0.374–1.011)

0.055

  1. CI confidence interval, G1 well differentiated, G2 moderately differentiated, G3 poorly differentiated, G4 undifferentiated, HR hazard ratio, PLNs positive lymph nodes, RLNs removes lymph nodes, RT radiotherapy