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Table 1 Patient, disease, and treatment characteristics

From: Patterns of locoregional failure following post-operative intensity-modulated radiotherapy to oral cavity cancer: quantitative spatial and dosimetric analysis using a deformable image registration workflow

Characteristic

N (%)

Age

 

Median (range)

59.5 years (22–87)

Gender

 Female

20 (37)

 Male

34 (63)

Tumor Site

 Oral Tongue

21 (39)

 Buccal Mucosa

10 (18.5)

 Floor of Mouth

2 (4)

 Hard Palate

3 (5)

 Gingiva

10 (18.5)

 Retromolar Trigone

8 (15)

Histologic Differentiation

 Poor

13 (24)

 Moderate

36 (67)

 Well

5 (9)

Clinical T stage

 T1

8 (15)

 T2

19 (35)

 T3

9 (17)

 T4

18 (33)

Clinical N stage

 Nx

2 (4)

 N0

23 (43)

 N1

11 (20)

 N2a

0 (0)

 N2b

14 (26)

 N2c

4 (7)

Pathological T stage

 ypT0

2 (4)

 T1

8 (15)

 T2

20 (37)

 T3

7 (13)

 T4

17 (31)

Pathological N stage

 No dissection

7 (13)

 N0

12 (22)

 N1

12 (22)

 N2a

0 (0)

 N2b

19 (36)

 N2c

4 (7)

Overall stage

 Stage I

1 (2)

 Stage II

6 (11)

 Stage III

7 (13)

 Stage IV

40 (74)

Primary Surgery Margin Status

 Negative (>5 mm)

41 (76)

 Close (≤ 5 mm)

9 (17)

 Positive

4 (7)

Depth of invasion

  ≤ 1.5 cm

33 (61)

  > 1.5 cm

18 (33)

 Unspecified

3 (6)

Perineural invasion

 Yes

22 (41)

 No

32 (59)

Lymphovascular invasion

 Yes

14 (26)

 No

30 (56)

 Unspecified

10 (18)

Extracapsular extension

 Yes

17 (31)

 No

37 (69)

IMRT dose and fractionation

 Median Dose (Range), in Gy

60 (56–70)

 Median Fractionation (Range)

30 (28–33)

Laterality of Neck radiation

 Unilateral

13 (24)

 Bilateral

41 (76)

Chemotherapy

 

 Induction

5 (9)

 Concurrent

13 (24)

 Induction and concurrent

2 (4)

 No chemotherapy

32 (59)