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Table 1 Patient, disease, and treatment characteristics

From: Patterns of locoregional failure following post-operative intensity-modulated radiotherapy to oral cavity cancer: quantitative spatial and dosimetric analysis using a deformable image registration workflow

Characteristic N (%)
Age  
Median (range) 59.5 years (22–87)
Gender
 Female 20 (37)
 Male 34 (63)
Tumor Site
 Oral Tongue 21 (39)
 Buccal Mucosa 10 (18.5)
 Floor of Mouth 2 (4)
 Hard Palate 3 (5)
 Gingiva 10 (18.5)
 Retromolar Trigone 8 (15)
Histologic Differentiation
 Poor 13 (24)
 Moderate 36 (67)
 Well 5 (9)
Clinical T stage
 T1 8 (15)
 T2 19 (35)
 T3 9 (17)
 T4 18 (33)
Clinical N stage
 Nx 2 (4)
 N0 23 (43)
 N1 11 (20)
 N2a 0 (0)
 N2b 14 (26)
 N2c 4 (7)
Pathological T stage
 ypT0 2 (4)
 T1 8 (15)
 T2 20 (37)
 T3 7 (13)
 T4 17 (31)
Pathological N stage
 No dissection 7 (13)
 N0 12 (22)
 N1 12 (22)
 N2a 0 (0)
 N2b 19 (36)
 N2c 4 (7)
Overall stage
 Stage I 1 (2)
 Stage II 6 (11)
 Stage III 7 (13)
 Stage IV 40 (74)
Primary Surgery Margin Status
 Negative (>5 mm) 41 (76)
 Close (≤ 5 mm) 9 (17)
 Positive 4 (7)
Depth of invasion
  ≤ 1.5 cm 33 (61)
  > 1.5 cm 18 (33)
 Unspecified 3 (6)
Perineural invasion
 Yes 22 (41)
 No 32 (59)
Lymphovascular invasion
 Yes 14 (26)
 No 30 (56)
 Unspecified 10 (18)
Extracapsular extension
 Yes 17 (31)
 No 37 (69)
IMRT dose and fractionation
 Median Dose (Range), in Gy 60 (56–70)
 Median Fractionation (Range) 30 (28–33)
Laterality of Neck radiation
 Unilateral 13 (24)
 Bilateral 41 (76)
Chemotherapy  
 Induction 5 (9)
 Concurrent 13 (24)
 Induction and concurrent 2 (4)
 No chemotherapy 32 (59)