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Table 2 Hazard ratios (HR) with 95%-confidence intervals (CI) in univariate analysis for OS, PFS and LR

From: Intensity-modulated versus 3-dimensional conformal radiotherapy in the definitive treatment of esophageal cancer: comparison of outcomes and acute toxicity

 

OS

PFS

LR

Parameter

HR [95% CI]

p-value

HR [95% CI]

p-value

HR [95% CI]

p-value

RT mode (IMRT vs. 3DCRT)

0.716 [0.430; 1.191]

0.198

0.830 [0.512; 1.344]

0.448

0.812 [0.356; 1.852]

0.620

Age (continuous)

1.006 [0.978; 1.035]

0.676

1.009 [0.981; 1.037]

0.525

0.962 [0.906; 1.022]

0.211

KPS (continuous)

1.004 [0.973; 1.035]

0.816

1.024 [0.992; 1.057]

0.138

0.988 [0.940; 1.039]

0.644

T-stage (T3/4 vs. T1/2)

1.177 [0.637; 2.178]

0.603

1.226 [0.679; 2.212]

0.499

1.170 [0.411; 3.328]

0.768

N-stage (N1-3 vs. N0)

1.493 [0.779; 2.863]

0.228

1.399 [0.764; 2.561]

0.277

1.218 [0.408; 3.635]

0.723

Grade (G3 vs. G1/2)

1.651 [0.996; 2.737]

0.052

1.518 [0.938; 2.456]

0.089

1.040 [0.455; 2.374]

0.926

Pretreatment Hemoglobin

0.930 [0.821; 1.054]

0.255

0.886 [0.783; 1.003]

0.057

0.975 [0.821; 1.157]

0.768

Location

1.002 [0.960; 1.046]

0.935

0.992 [0.952; 1.033]

0.689

1.030 [0.958; 1.107]

0.422

Histology (Adeno vs. SCC)

1.555 [0.786; 3.076]

0.205

1.630 [0.851; 3.125]

0.141

1.354 [0.489; 3.750]

0.560

RT dose (continuous)

0.946 [0.881; 1.015]

0.122

0.955 [0.893; 1.021]

0.173

0.763 [0.635; 0.916]

0.004

Treatment year (continuous)

1.021 [0.934; 1.116]

0.646

1.043 [0.958; 1.135]

0.329

1.041 [0.893; 1.213]

0.606

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Radiation Oncology

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