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Table 5 Univariate and multiple Cox regression analysis of factors associated with biochemical recurrence-free survival

From: Risk adapted dose-intensified postoperative radiation therapy in prostate cancer patients using a simultaneous integrated boost technique applied with helical Tomotherapy

Factor

RR

CI

p

Univariate Cox regression:

   

 Age: ≤65 versus >65 (years)

1.004

0.224–4.495

0.995

 ECOG performance status: 0 versus >1

0.898

0.105–7.692

0.922

 Lymphnode involvement: N0 versus N1

0.476

0.057–3.956

0.492

 Gleason score: ≤7 versus ≥8

2.224

0.496–9.976

0.297

 Surgical margins: R0 versus R1

0.558

0.125–2.496

0.445

 Androgen deprivation therapy: no or yes

0.91

0.175–4.741

0.911

 Pelvic nodal RT: no or yes

0.635

0.076–5.288

0.674

 Presurgery PSA: ≤10 versus >10 (ng/ml)

6.537

0.785–54.411

0.082

 PSA Persistance after surgery: <0.5 versus ≥0.5 (ng/ml)

4.623

1.029–20.781

0.046

 PSA at start of RT <0.5 versus ≥0.5 (ng/ml)

2.980

0.659–13.473

0.156

Multivariate Cox regression:

   

 Presurgery PSA: ≤10 versus >10 (ng/ml)

4.402

0.474–40.891

0.192

 PSA Persistance after surgery: <0.5 versus ≥0.5 (ng/ml)

2.724

0.556–13.337

0.216

  1. Abbreviations: RR relative risk, CI 95% confidence intervals, RT radiation therapy, p p-value, ECOG Eastern Cooperative Oncology Group, PSA prostate specific antigen