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Table 4 Distribution of brain metastases in HA region for SCLC patients

From: Analyses of distribution and dosimetry of brain metastases in small cell lung cancer with relation to the neural stem cell regions: feasibility of sparing the hippocampus in prophylactic cranial irradiation

Study

Kundapur et al. [8]

Gondi et al. [9]

Ghia et al. [10]

Marsh et al. [11]

Wan et al. [12]

Harth et al. [13]

No of metastatic lesions

NA

1131

272

697

2270

856

No of pts

NA

371

100

107

488

100

No of metastases in HA region (%)

NA

34 (3.0%)

9 (3.3%)

16 (2.3%)

7 (0.3%)

11 (1.3%)

No of pts. with metastases in HA region (%)

NA

22 (8.6%)

8 (8.0%)

16 (15.0%)

7 (1.4%)

11 (11.0%)

No of metastatic lesions for SCLC pts

359

NA

24

145

225

201

No of SCLC pts

59

38

10

11

44

11

No of metastases in HA region for SCLC pts. (%)

3 (0.8%)

NA

3 (12.5%)

3 (2.1%)

1 (0.4%)

5 (2.5%)

No of SCLC pts. with metastases in HA region (%)

3 (5.1%)

4 (10.5%)

3 (30.0%)

3 (27.3%)

1 (2.3%)

5 (45.5%)

  1. pts patients, HA hippocampal avoidance, SCLC small cell lung cancer, NA not available