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Table 3 Univariate analysis of prognostic factors for overall survival (log-rank test)

From: Validation of the graded prognostic assessment for lung cancer with brain metastases using molecular markers (lung-molGPA)

Parameter

Median survival in months

p-value

Male gender

5.5

 

Female gender

5.0

0.49

Adenocarcinoma

5.6

 

Non-adenocarcinoma

4.5

0.87

Extracranial metastases

4.4

 

No extracranial metastases

7.5

0.0001

1–4 brain metastases

6.0

 

>4 brain metastases

4.6

0.04

EGFR or ALK positive

22.9

 

Not EGFR or ALK positive

5.0

0.0001

Age <70 years

6.0

 

Age ≥70 years

3.0

0.006

KPS ≤70

2.5

 

KPS 80

7.0

 

KPS 90–100

11.0

0.0001

  1. KPS Karnofsky performance status