Table 2 Multivariate analysis of predictors for OS and LCSS

 60–79 years

0.822 (0.742–0.911)

0.000

0.809 (0.723–0.904)

0.000

0.758 (0.648–0.887)

0.001

0.716 (0.604–0.850)

0.000

 ≥80 years

1.007 (0.844–1.201)

0.938

1.059 (0.878–1.277)

0.548

0.962 (0.730–1.267)

0.781

0.977 (0.727–1.313)

0.876

Gender (versus Male)

1.066 (0.974–1.168)

0.163

1.049 (0.951–1.158)

0.337

1.030 (0.895–1.186)

0.676

1.030 (0.884–1.202)

0.703

Race (versus White)

1.033 (0.923–1.157)

0.570

1.043 (0.922–1.179)

0.504

1.085 (0.912–1.291)

0.357

1.108 (0.917–1.339)

0.289

Marital status (versus Married)

1.001 (0.912–1.099)

0.984

0.966 (0.872–1.070)

0.511

1.160 (1.000–1.344)

0.049

1.173 (0.999–1.378)

0.052

Insurance (versus insured)

0.970 (0.883–1.065)

0.519

0.995 (0.899–1.101)

0.924

0.844 (0.730–0.977)

0.023

0.877 (0.748–1.027)

0.104

Laterality (versus left)

1.021 (0.929–1.121)

0.671

1.061 (0.958–1.175)

0.257

1.048 (0.906–1.212)

0.530

1.107 (0.943–1.298)

0.213

 Lower lobe

1.025 (0.812–1.294)

0.834

1.027 (0.800–1.317)

0.835

1.137 (0.807–1.601)

0.463

1.076 (0.737–1.570)

0.706

 Middle lobe

1.059 (0.960–1.167)

0.251

1.024 (0.921–1.139)

0.660

0.996 (0.857–1.158)

0.961

0.958 (0.813–1.130)

0.612

Tumor size

1.005 (1.003–1.008)

0.000

1.006 (1.003–1.008)

0.000

1.007 (1.003–1.012)

0.000

1.009 (1.005–1.014)

0.000

Regional LN positive

1.034 (1.014–1.054)

0.001

1.040 (1.019–1.062)

0.000

1.053 (1.020–1.087)

0.002

1.069 (1.033–1.107)

0.000

Regional LN examined

0.995 (0.987–1.004)

0.261

0.993 (0.984–1.002)

0.136

0.994 (0.981–1.007)

0.370

0.988 (0.973–1.003)

0.121

% of LN positive

1.902 (1.490–2.429)

0.000

1.965 (1.507–2.562)

0.000

1.562 (1.041–2.342)

0.031

1.560 (0.997–2.439)

0.051

 Squamous cell carcinoma

1.183 (1.058–1.323)

0.003

1.133 (1.002–1.282)

0.046

1.278 (1.077–1.516)

0.005

1.213 (1.004–1.467)

0.045

 Adenosquamous and Large cell carcinoma

1.278 (1.069–1.527)

0.007

1.300 (1.073–1.575)

0.007

1.256 (0.964–1.637)

0.092

1.335 (1.007–1.771)

0.045

 Moderately differentiated

1.118 (0.901–1.387)

0.310

1.149 (0.906–1.458)

0.251

1.051 (0.703–1.570)

0.809

1.117 (0.717–1.741)

0.625

 Poorly differentiated

1.245 (1.002–1.546)

0.048

1.284 (1.011–1.631)

0.041

1.168 (0.781–1.745)

0.449

1.238 (0.794–1.929)

0.346

 Undifferentiated

1.371 (0.969–1.942)

0.075

1.377 (0.940–2.018)

0.101

1.434 (0.799–2.571)

0.227

1.526 (0.809–2.880)

0.192

 Lobectomy

0.786 (0.664–0.930)

0.005

0.769 (0.641–0.922)

0.005

0.659 (0.500–0.868)

0.003

0.613 (0.456–0.825)

0.001

 Pneumonectomy

0.778 (0.619–0.978)

0.032

0.757 (0.590–0.970)

0.028

0.515 (0.344–0.771)

0.001

0.487 (0.315–0.753)

0.001

 T2

1.224 (1.090–1.375)

0.001

1.224 (1.078–1.390)

0.002

1.165 (0.971–1.397)

0.100

1.160 (0.950–1.417)

0.145

 T3

1.816 (1.477–2.233)

0.000

1.960 (1.574–2.440)

0.000

1.747 (1.249–2.443)

0.001

1.812 (1.263–2.598)

0.001

PORT (versus No PORT)

0.846 (0.769–0.932)

0.001

0.838 (0.755–0.931)

0.001

0.793 (0.690–0.912)

0.001

0.837 (0.719–0.975)

0.022