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Table 1 Demographics and clinical characteristics for patients treated with and without PORT before and after PSM

From: Propensity score-matching analysis of postoperative radiotherapy for stage IIIA-N2 non-small cell lung cancer using the Surveillance, Epidemiology, and End Results database

Demographic or clinical characteristic

Before PSM

After PSM

No PORT

(N = 2090)

PORT (N=1244)

P

No PORT

(N = 744)

PORT

(N = 744)

P

Age, years (range)

65.5 (22–89)

65.7 (28–93)

0.581

66.4 (62–89)

65.7 (28–90)

0.692

Gender

 Male

1026 (62.0%)

629 (38.0%)

0.411

355 (48.2%)

381 (51.8%)

0.178

 Female

1064 (63.4%)

615 (36.6%)

389 (51.7%)

363 (48.3%)

Race

 White

1689 (62.8%)

999 (37.2%)

0.720

604 (49.9%)

607 (50.1%)

0.842

 Nonwhite

401 (62.1%)

245 (37.9%)

140 (50.5%)

137 (49.5%)

Marital status

 Married

1185 (59.4%)

810 (50.6%)

0.000

465 (50.6%)

454 (49.4%)

0.557

 others

905 (67.6%)

434 (32.4%)

279 (49.0%)

290 (51.0%)

Insurance

 Insured

1261 (61.7%)

783 (38.3%)

0.135

462 (49.5%)

471 (50.5%)

0.629

 others

829 (64.3%)

461 (35.7%)

282 (50.8%)

273 (49.2%)

Laterality

 Left

976 (63.9%)

552 (36.1%)

0.192

317 (47.7%)

347 (52.3%)

0.118

 Right

1114 (61.7%)

692 (38.3%)

427 (51.8%)

397 (48.2%)

Location

 Upper lobe

1229 (61.5%)

768 (38.5%)

0.084

436 (48.9%)

455 (51.1%)

0.587

 Middle lobe

89 (58.9%)

62 (41.1%)

36 (52.9%)

32 (47.1%)

 Lower lobe

772 (65.1%)

414 (34.9%)

272 (51.4%)

257 (48.6%)

Tumor size, cm (range)

3.8 (0.1–19.0)

3.7 (0.5–15)

0.340

3.7 (0.1–15)

3.8 (0.5–15)

0.670

LN positive (range)

3.4 (1–41)

3.8 (1–30)

0.000

3.4 (1–33)

3.5 (1–24)

0.062

LN examined (range)

12.2 (1–90)

11.6 (1–64)

0.006

11.9 (1–68)

12.0 (1–61)

0.473

% of LN positive (range)

35.4 (1.4–100)

41.2 (1.7–100)

0.000

35.5 (1.4–100)

35.8 (1.7–100)

0.380

Histology

 Adenocarcinoma

1423 (61.5%)

891 (38.5%)

0.097

478 (48.1%)

515 (51.9%)

0.110

 Squamous cell carcinoma

505 (65.2%)

270 (34.8%)

204 (54.4%)

171 (45.6%)

 Adenosquamous and large cell carcinoma

162 (66.1%)

83 (33.9%)

62 (51.7%)

58 (48.3%)

Differentiation

 Well differentiated

131 (72.4%)

50 (27.6%)

0.012

20 (40.8%)

29 (59.2%)

0.548

 Moderately differentiated

930 (61.5%)

581 (38.5%)

354 (51.1%)

339 (48.9%)

 Poorly differentiated

969 (62.2%)

589 (37.8%)

354 (49.7%)

358 (50.3%)

 Undifferentiated

60 (71.4%)

24 (28.6%)

16 (47.1%)

18 (52.9%)

Surgical procedure

 Sublobectomy

145 (51.4%)

137 (48.6%)

0.000

50 (51.0%)

48 (49.0%)

0.972

 Lobectomy

1741 (62.9%)

1026 (37.1%)

643 (49.9%)

646 (50.1%)

 Pneumonectomy

204 (71.6%)

81 (28.4%)

51 (50.5%)

50 (49.5%)

T stage (sixth edition)

 T1

629 (61.3%)

397 (38.7%)

0.359

235 (50.6%)

229 (49.4%)

0.908

 T2

1341 (63.6%)

768 (36.4%)

468 (49.8%)

471 (50.2%)

 T3

120 (60.3%)

79 (39.7%)

41 (48.2%)

44 (51.8%)

  1. LN lymph node, PSM propensity score-matching, PORT postoperative radiotherapy