High-biologically effective dose palliative radiotherapy for a tumor thrombus might improve the long-term prognosis of hepatocellular carcinoma: a retrospective study

Table 3 Multivariate analysis of overall survival

Variables		n	HR (95% CI)	P
Gender	Male/Female	75/5	3.982(1.178–13.462)	0.26
RT	A-RT/2D-RT/Non-RT	54/10/16	3.982(1.178–13.462)	0.198
RT	A-RT/Non-RT 2D-RT/Non-RT	54/16 10/16	0.954(0.187–4.862) 2.135(0.365–12.478)	0.955 0.400
BED, Gy	≥58.9/<58.9/0 Gy	42/22/16		0.039
BED, Gy	≥58.9/0 Gy <58.9/0 Gy	42/16 22/16	0.390(0.075–2.034) 0.971(0.175–5.388)	0.264 0.973
Types Child Pugh classification PS (ECOG) TBIL, μmol/L	I + II/III + IV A/B 0–1/2–3 ≥20/<20	40/40 50/30 59/21 34/46	1.363(1.033–1.798) 1.992(1.115–3.558) 2.820(1.401–5.673) 1.029(0.568–1.866)	0.029 0.020 0.004 0.925

A-RT accurate radiotherapy, 2D-RT two-dimensional radiotherapy, Non-RT non-radiotherapy, BED biologically effective dose, Types types of tumor thrombus, TBIL total bilirubin, CI confidence interval, HR hazard ratio

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