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Table 5 Univariate analysis of average dosimetric parameters

From: Prognostic analysis of radiation pneumonitis: carbon-ion radiotherapy in patients with locally advanced lung cancer

Parameters

≥ grade 2

(min - max)

grade 0–1

(min - max)

p value

PTV (cm3)

448.5

(155.8–712.7)

371.0

(73.8–1319.8)

0.193

MLD (Gy RBE)

12.0

(6.5–17.0)

9.0

(2.9–16.2)

0.023

V5 (%)

33.8

(17.9–49.0)

24.9

(7.0–46.1)

0.034

V10 (%)

30.6

(15.3–46.2)

22.6

(6.5–42.6)

0.045

V20 (%)

24.5

(10.1–31.4)

17.9

(5.6–36.7)

0.039

V30 (%)

19.0

(10.1–31.4)

12.9

(3.7–23.6)

0.015

V40 (%)

12.2

(5.2–18.1)

8.8

(3.1–18.9)

0.052

V50 (%)

6.7

(2.6–13.3)

5.8

(2.1–14.2)

0.442

  1. PTV planning target volume, MLD mean lung dose, RBE relative biological effectiveness, V X volume of lung receiving ≥ X Gy (RBE)