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Table 3 Predictive cutoff value of spleen dosimetric variables and its determining ability to Min ALC

From: Radiation-related lymphopenia is associated with spleen irradiation dose during radiotherapy in patients with hepatocellular carcinoma

Parameters

Threshold

Accuracy

OR

95% CI

MSD

227.72 cGy

77.70%

14.39

12.18 to 16.60

V5

17.84%

75.90%

7.99

6.91 to 9.07

V25

0.98%

74.30%

0.77

0.08 to 1.46

V30

0.42%

77.70%

0.53

−0.13 to 1.19

  1. MSD mean dose of spleen, V x volumetric proportion of spleen receiving ≥ x Gy, Min ALC minimum absolute lymphocyte counts during radiotherapy, OR odds ratio, CI confidence interval