Is it possible for knowledge-based planning to improve intensity modulated radiation therapy plan quality for planners with different planning experiences in left-sided breast cancer patients?

Table 2 The summary of the quantitative analysis of the OARs sparing for the entire evaluation group for each planner

Planner	Plan	Heart				Ipsilateral lung				Contralateral breast	Contralateral lung
Planner	Plan	V₅ (%)	V₂₀ (%)	V₃₀ (%)	Mean dose (Gy)	V₅ (%)	V₂₀ (%)	V₃₀ (%)	Mean dose (Gy)	Mean dose (Gy)	Mean dose (Gy)
Beginner planner A	Manual plan	39.80	10.89	5.73	7.50	58.13	18.42	12.09	11.60	0.43	0.20
	KBP plan	36.87	7.49	4.23	6.62	51.56	16.59	11.15	11.43	0.47	0.20
	p value	0.002	<0.0001	0.001	<0.0001	<0.0001	0.001	0.01	0.33	0.32	0.95
Beginner planner B	Manual plan	39.37	11.28	6.03	7.52	58.15	18.31	12.12	11.85	0.47	0.20
	KBP plan	37.73	7.80	4.13	6.63	53.46	16.21	10.52	11.47	0.48	0.16
	p value	0.30	<0.0001	<0.0001	<0.0001	0.01	0.002	0.004	0.21	0.20	0.06
Junior planner A	Manual plan	36.46	10.25	5.33	6.99	52.3	19.16	12.82	11.70	0.49	0.17
	KBP plan	33.85	9.73	5.30	6.61	50.52	18.88	12.49	11.51	0.43	0.17
	p value	<0.0001	0.04	0.87	<0.0001	0.03	0.32	0.44	0.41	0.18	0.17
Junior planner B	Manual plan	35.36	10.41	5.54	7.00	53.75	18.56	11.94	11.78	0.41	0.17
	KBP plan	34.63	9.63	5.20	6.6	51.92	17.98	11.75	11.41	0.41	0.17
	p value	0.23	0.02	0.04	<0.0001	0.02	0.10	0.42	0.05	0.88	0.82
Senior planner A	Manual plan	36.58	8.00	4.53	6.72	53.76	18.51	12.76	11.79	0.46	0.22
	KBP plan	37.80	7.76	4.64	6.63	54.42	18.63	12.73	11.94	0.47	0.19
	p value	0.06	0.23	0.41	0.14	0.39	0.70	0.91	0.48	0.24	0.27
Senior planner B	Manual plan	36.78	7.98	4.59	6.70	54.07	17.97	12.16	11.74	0.47	0.21
	KBP plan	37.00	7.74	4.58	6.55	54.32	17.8	12.07	11.73	0.47	0.19
	p value	0.71	0.40	0.90	0.02	0.77	0.60	0.68	0.98	0.70	0.15

ISSN: 1748-717X