Table 4 OAR sparing comparison
From: Dosimetric advantage of volumetric modulated arc therapy in the treatment of intraocular cancer
OAR | CRT | IMRT | VMAT | P-value | ||
|---|---|---|---|---|---|---|
CRT vs IMRT | CRT vs VMAT | IMRT vs VMAT | ||||
Ipsilateral lens | ||||||
D1(cGy) | 4809.54 ± 524.60 | 2972.66 ± 1407.12 | 3317.82 ± 915.28 | <0.01 | <0.01 | 0.50 |
EUD(cGy) | 4339.37 ± 811.97 | 2299.64 ± 787.15 | 2390.57 ± 733.59 | <0.01 | <0.01 | 0.30 |
NTCP | 0.95 ± 0.08 | 0.65 ± 0.26 | 0.70 ± 0.26 | <0.01 | <0.01 | 0.13 |
Ipsilateral eyeball | ||||||
Dmean(cGy) | 4558.41 ± 455.76 | 3071.33 ± 920.03 | 3087.5 ± 386.25 | <0.01 | <0.01 | 0.23 |
D1(cGy) | 5253.86 ± 162.60 | 4976.07 ± 1321.53 | 5239.64 ± 130.72 | 0.46 | 0.82 | 0.46 |
EUD(cGy) | 4922.18 ± 223.88 | 4680.53 ± 159.80 | 4579.88 ± 217.23 | <0.01 | <0.01 | 0.02 |
NTCP | 0.10 ± 0.04 | 0.07 ± 0.02 | 0.06 ± 0.02 | <0.01 | <0.01 | 0.02 |
Contralateral lens | ||||||
D1(cGy) | 272.18 ± 345.84 | 946.63 ± 1314.73 | 382.71 ± 110.54 | 0.10 | 0.23 | 0.13 |
EUD(cGy) | 217.28 ± 296.92 | 211.97 ± 129.58 | 299.96 ± 89.88 | 0.95 | 0.29 | 0.02 |
Contralateral eyeball | ||||||
Dmean(cGy) | 214.77 ± 279.60 | 462.76 ± 900.98 | 436.87 ± 186.89 | 0.35 | <0.01 | 0.89 |
D1(cGy) | 412.96 ± 508.90 | 887.93 ± 1324.14 | 978.18 ± 445.59 | 0.23 | <0.01 | 0.80 |
EUD(cGy) | 346.45 ± 422.16 | 448.63 ± 315.48 | 798.11 ± 361.61 | 0.31 | <0.01 | <0.01 |
Brainstem | ||||||
D1(cGy) | 2615.36 ± 1026.22 | 1820.59 ± 709.32 | 1401.00 ± 606.04 | 0.02 | <0.01 | <0.01 |
EUD(cGy) | 2029.99 ± 905.89 | 1321.18 ± 552.40 | 1001.44 ± 421.73 | 0.01 | <0.01 | <0.01 |
Optic nerves | ||||||
D1(cGy) | 4886.14 ± 644.38 | 4444.54 ± 825.25 | 4532.32 ± 854.19 | 0.03 | 0.07 | 0.57 |
EUD | 3356.65 ± 665.49 | 2592.39 ± 719.44 | 2973.78 ± 772.57 | <0.01 | 0.03 | 0.03 |
Optic chiasm | ||||||
D1(cGy) | 1513.89 ± 1082.09 | 1442.11 ± 1264.59 | 1456.07 ± 892.92 | 0.87 | 0.86 | 0.97 |
EUD(cGy) | 2256.45 ± 907.36 | 1646.8 ± 995.51 | 1396.54 ± 646.45 | 0.04 | 0.04 | 0.25 |