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Table 4 Planning target volumes for 6 patients in the 45-patient VMAT cohort with both IMRT and VMAT plans

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

 

Median (Range)

IMRT

VMAT

P*

bPTV

 Dmin (Gy)

58.9 (55.6–59.7)

58.8 (57.2–60.0)

0.12

 Dmean (Gy)

62.0 (61.7–62.3)

62.1 (61.9–62.6)

0.83

 Dmax (Gy)

63.9 (63.2–65.8)

63.7 (63.1–64.7)

0.35

 V60Gy (%)

99.8 (97.8–100.0)

99.7 (98.7–100.0)

0.17

 II (Gy)

2.0 (1.3–2.4)

1.8 (1.1–2.4)

0.35

PTV

 Dmin(Gy)

45.4 (40.8–47.9)

41.2 (35.2–45.4)

0.03

 Dmean (Gy)

56.7 (55.7–58.0)

56.1 (54.7–57.8)

0.03

 Dmax (Gy)

63.9 (63.2–65.8)

63.7 (63.1–64.7)

0.35

 V50Gy (%)

98.5 (95.8–99.8)

96.7 (95.9–98.9)

0.12

 II (Gy)

11.4 (10.9–12.0)

11.8 (11.6–12.5)

0.17

  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy, D min minimum dose, D mean mean dose, D max maximum dose, V XXGy volume receiving XX Gy or more, II inhomogeneity index
  2. *From Wilcoxon signed rank sum analysis