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Table 4 Planning target volumes for 6 patients in the 45-patient VMAT cohort with both IMRT and VMAT plans

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

  Median (Range)
IMRT VMAT P*
bPTV
 Dmin (Gy) 58.9 (55.6–59.7) 58.8 (57.2–60.0) 0.12
 Dmean (Gy) 62.0 (61.7–62.3) 62.1 (61.9–62.6) 0.83
 Dmax (Gy) 63.9 (63.2–65.8) 63.7 (63.1–64.7) 0.35
 V60Gy (%) 99.8 (97.8–100.0) 99.7 (98.7–100.0) 0.17
 II (Gy) 2.0 (1.3–2.4) 1.8 (1.1–2.4) 0.35
PTV
 Dmin(Gy) 45.4 (40.8–47.9) 41.2 (35.2–45.4) 0.03
 Dmean (Gy) 56.7 (55.7–58.0) 56.1 (54.7–57.8) 0.03
 Dmax (Gy) 63.9 (63.2–65.8) 63.7 (63.1–64.7) 0.35
 V50Gy (%) 98.5 (95.8–99.8) 96.7 (95.9–98.9) 0.12
 II (Gy) 11.4 (10.9–12.0) 11.8 (11.6–12.5) 0.17
  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy, D min minimum dose, D mean mean dose, D max maximum dose, V XXGy volume receiving XX Gy or more, II inhomogeneity index
  2. *From Wilcoxon signed rank sum analysis