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Table 2 Planning target volumes for the 90-patient cohort

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

 

Median (Range)

IMRT

VMAT

P*

bPTV

 Dmin (Gy)

56.8 (48.4–59.8)

58.2 (49.4–60.0)

0.15

 Dmean (Gy)

61.8 (61.1–62.5)

61.9 (61.1–62.8)

0.02

 Dmax (Gy)

64.1 (62.6–66.4)

63.8 (62.0–65.5)

0.05

 V60Gy (%)

99.0 (90.5–100.0)

99.4 (94.7–100.0)

0.19

 II (Gy)

2.2 (1.2–5.3)

1.9 (0.8–3.1)

0.04

PTV

 Dmin(Gy)

45.3 (33.6–48.7)

42.7 (23.9–48.1)

0.003

 Dmean (Gy)

56.9 (53.8–58.7)

56.4 (54.2–59.3)

<0.001

 Dmax (Gy)

64.1 (62.6–66.7)

63.8 (62.0–65.5)

0.05

 V50Gy (%)

99.1 (95.1–99.9)

98.5 (95.2–99.9)

0.02

 II (Gy)

11.2 (9.8–12.7)

11.6 (10.2–12.5)

0.07

  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy, D min minimum dose, D mean mean dose, D max maximum dose, V XXGy volume receiving XX Gy or more, II inhomogeneity index
  2. *From Wilcoxon-Mann–Whitney rank sum analysis