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Table 2 Planning target volumes for the 90-patient cohort

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

  Median (Range)
IMRT VMAT P*
bPTV
 Dmin (Gy) 56.8 (48.4–59.8) 58.2 (49.4–60.0) 0.15
 Dmean (Gy) 61.8 (61.1–62.5) 61.9 (61.1–62.8) 0.02
 Dmax (Gy) 64.1 (62.6–66.4) 63.8 (62.0–65.5) 0.05
 V60Gy (%) 99.0 (90.5–100.0) 99.4 (94.7–100.0) 0.19
 II (Gy) 2.2 (1.2–5.3) 1.9 (0.8–3.1) 0.04
PTV
 Dmin(Gy) 45.3 (33.6–48.7) 42.7 (23.9–48.1) 0.003
 Dmean (Gy) 56.9 (53.8–58.7) 56.4 (54.2–59.3) <0.001
 Dmax (Gy) 64.1 (62.6–66.7) 63.8 (62.0–65.5) 0.05
 V50Gy (%) 99.1 (95.1–99.9) 98.5 (95.2–99.9) 0.02
 II (Gy) 11.2 (9.8–12.7) 11.6 (10.2–12.5) 0.07
  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy, D min minimum dose, D mean mean dose, D max maximum dose, V XXGy volume receiving XX Gy or more, II inhomogeneity index
  2. *From Wilcoxon-Mann–Whitney rank sum analysis