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Table 1 Characteristics of the 90-patient cohort

From: Sparing of normal tissues with volumetric arc radiation therapy for glioblastoma: single institution clinical experience

Characteristic Number of patients/Median value (Range) P*
IMRT VMAT
Diagnosis 0.49
 Glioblastoma 44 43  
 Oligodendroglioma 1 0
 Astrocytoma 0 2
Tumor Location 0.32
 Frontal 14 23  
 Occipital 2 1
 Parietal 8 6
 Temporal 13 6
 Thalamus 1 1
 2 or more lobes 7 8
Tumor Side 0.34
 Bilateral 4 5  
 Left 24 17
 Right 17 23
bPTV Volume (cc) 85.1 (11.0–328.5) 81.4 (28.3–285.3) 0.94
PTV Volume (cc) 359.3 (128.9–779.1) 370.8 (193.9–877.5) 0.18
Brain Volume (cc) 1301.5 (1022.2–1849.0) 1326.9 (1016.0–1658.6) 0.23
# Beams <0.001
 2 0 38  
 3 0 7
 5 43 0
 6 2 0
# Couch Angles <0.001
 1 0 39  
 2 0 6
 4 45 0
Multileaf Collimator 0.02
 High Definition 33 42  
 Standard 12 3
# Monitor Units 347 (285–487) 453 (274–665) <0.001
Treatment Time 15.0 (7.7–21) 10.0 (6.3–15.3) <0.001
  1. IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy
  2. *From Fisher’s exact test or Wilcoxon-Mann–Whitney rank sum analysis