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Table 2 Cox regression analysis

From: Does age really matter? Radiotherapy in elderly patients with glioblastoma, the Munich experience

Cox regression

HR

95% CI

p

Age (older vs. younger than 69.6 years)

1.44

0.81–2.54

0.216

ECOG ( 2–3 vs. 0–1)

2.35

1.28–4.34

0.008

MGMT (negative vs. positive)a

2.63

1.04–6.66

0.03

Extent of resection ( GTR vs. STR & Biopsy )

0.47

0.25–0.876

0.014

Ischemia (ischemia vs. no ischemia)b

1.94

0.98–3.82

0.059

Time from surgery to RTx (earlier vs. later than 28 days)

1.07

0.61–1.89

0.816

Adjuvant CHT vs. No Adjuvant CHT

0.24

0.13–0.47

<0.001

RCHT vs. RT

0.38

0.21–0.69

0.002

Treatment for recurrent disease (Treatment vs. BSC)c

0.06

0.02–0.17

<0.001

  1. aonly patients with measured MGMT methylation; bonly patients with postoperative imaging including DWI b1000 and ADC; conly patients with recurrence diagnosed by imaging