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Table 2 Cox regression analysis

From: Does age really matter? Radiotherapy in elderly patients with glioblastoma, the Munich experience

Cox regression HR 95% CI p
Age (older vs. younger than 69.6 years) 1.44 0.81–2.54 0.216
ECOG ( 2–3 vs. 0–1) 2.35 1.28–4.34 0.008
MGMT (negative vs. positive)a 2.63 1.04–6.66 0.03
Extent of resection ( GTR vs. STR & Biopsy ) 0.47 0.25–0.876 0.014
Ischemia (ischemia vs. no ischemia)b 1.94 0.98–3.82 0.059
Time from surgery to RTx (earlier vs. later than 28 days) 1.07 0.61–1.89 0.816
Adjuvant CHT vs. No Adjuvant CHT 0.24 0.13–0.47 <0.001
RCHT vs. RT 0.38 0.21–0.69 0.002
Treatment for recurrent disease (Treatment vs. BSC)c 0.06 0.02–0.17 <0.001
  1. aonly patients with measured MGMT methylation; bonly patients with postoperative imaging including DWI b1000 and ADC; conly patients with recurrence diagnosed by imaging