Skip to main content

Table 3 Dosimetric results of all plans

From: RapidPlan head and neck model: the objectives and possible clinical benefit

Structure

Parameter

Clinical plan

RP_OR_2P_33

RP_OR_1P_33

RP_2A_2P_33

RP_OR_2P_30

PTV_boost

D2% [%]

103.5 ± 0.9

103.2 ± 0.8

103.3 ± 0.8

103.6 ± 0.8

103.2 ± 0.8

p1 = 0.058

p2 = 0.466

p3 = 0.003

p4 = 0.459

p5 = 0.843

 

D98% [%]

93.3 ± 1.6

94.4 ± 1.4

94.3 ± 1.5

93.6 ± 1.4

94.6 ± 1.5

p1 = 0.002

p2 = 0.304

p3 < 0.001

p4 = 0.017

p5 = 0.341

PTV_elective

D2% [%]

108.8 ± 5.2

105.7 ± 1.2

105.8 ± 1.2

106. ±1.1

105.1 ± 0.8

p1 = 0.008

p2 = 0.272

p3 = 0.001

p4 < 0.001

p5 = 0.038

 

D98% [%]

93.6 ± 1.8

92.8 ± 1.8

92.8 ± 2.1

91.4 ± 1.5

92.3 ± 1.8

p1 = 0.077

p2 = 0.986

p3 < 0.001

p4 < 0.001

p5 < 0.001

 

Mean [Gy]

55.1 ± 0.6

54.4 ± 0.3

54.4 ± 0.4

54.4 ± 0.4

53.9 ± 0.3

p1 < 0.001

p2 = 0.701

p3 = 0.366

p5 < 0.001

Spinal Cord

Dmax [Gy]

39.1 ± 7.3

32.0 ± 3.9

31.8 ± 3.9

33.1 ± 3.4

29.3 ± 3.2

p1 < 0.001

p2 = 0.058

p3 = 0.001

p4 = 0.048

p5 = 0.001

Brain Stem

Dmax [Gy]

37.9 ± 15.1

31.0 ± 13.4

31.1 ± 13.5

30.8 ± 13.5

29.8 ± 12.1

p1 = 0.023

p2 = 0.757

p3 = 0.864

p4 = 0.515

p5 = 0.022

Oral Cavity

Mean [Gy]

45.4 ± 9.3

40.2 ± 11.1

40.2 ± 11.0

41.3 ± 10.5

38.2 ± 10.2

p1 < 0.001

p2 = 0.839

p3 = <0.001

p4 = 0.013

p5 < 0.001

Parotids

Mean [Gy]

27.1 ± 6.0

24.9 ± 5.4

24.9 ± 5.2

25.2 ± 5.4

23.8 ± 4.9

p1 < 0.001

p2 = 0.978

p3 = 0.063

p4 = 0.003

p5 < 0.001

Larynx

Mean [Gy]

35.6 ± 7.4

25.7 ± 5.5

25.8 ± 5.6

26.9 ± 5.8

24.8 ± 5.2

p1 < 0.001

p2 = 0.734

p3 = 0.005

p4 < 0.001

p5 < 0.001

Thyroid

Mean [Gy]

45.6 ± 7.2

44.0 ± 6.6

44.1 ± 6.5

44.8 ± 6.4

42.0 ± 6.3

p1 = 0.094

p2 = 0.542

p3 < 0.001

p4 < 0.001

p5 = 0.358

Eyes

Mean [Gy]

3.9 ± 3.3

2.9 ± 1.6

3.0 ± 1.6

3.1 ± 1.5

2.8 ± 1.4

p1 = 0.036

p2 = 0.618

p3 = 0.253

p4 = 0.229

p5 = 0.071

Constrictors

Mean [Gy]

58.1 ± 12.3

55.2 ± 15.3

55.3 ± 15.2

55.7 ± 14.7

52.2 ± 14.6

p1 < 0.001

p2 = 0.236

p3 = 0.006

p4 = 0.293

p5 < 0.001

Submandibulars

Mean [Gy]

63.9 ± 6.3

63.8 ± 6.8

63.8 ± 6.8

63.9 ± 6.8

61.0 ± 5.4

p1 = 0.399

p2 = 0.598

p3 = 0.010

p4 < 0.001

p5 = 0.866

(Body-PTV)/PTV

V_20Gy/V_PTV

3.32 ± 0.48

2.74 ± 0.46

2.75 ± 0.47

2.67 ± 0.45

2.57 ± 0.44

p1 < 0.001

p2 = 0.125

p3 = 0.009

p5 < 0.001

 

V_35Gy/V_PTV

1.46 ± 0.28

1.07 ± 0.24

1.08 ± 0.24

1.07 ± 0.22

0.97 ± 0.21

p1 < 0.001

p2 = 0.002

p3 = 0.881

p5 < 0.001

  1. p1 = p-value between RP_OR_2P_33 and CP (RapidPlan)
  2. p2 = p-value between RP_OR_1P_33 and RP_OR_2P_33 (different model)
  3. p3 = p-value between RP_2A_2P_33 and RP_OR_2P_33 (arc geometry)
  4. p4 = p-value between RP_OR_2P_30 and RP_OR_2P_33 (fractionation)
  5. p5 = p-value between RP_2A_2P_33 and CP (arc geometry)