From: RapidPlan head and neck model: the objectives and possible clinical benefit
Structure | Parameter | Clinical plan | RP_OR_2P_33 | RP_OR_1P_33 | RP_2A_2P_33 | RP_OR_2P_30 |
---|---|---|---|---|---|---|
PTV_boost | D2% [%] | 103.5 ± 0.9 | 103.2 ± 0.8 | 103.3 ± 0.8 | 103.6 ± 0.8 | 103.2 ± 0.8 |
p1 = 0.058 | p2 = 0.466 | p3 = 0.003 | p4 = 0.459 | |||
p5 = 0.843 | ||||||
D98% [%] | 93.3 ± 1.6 | 94.4 ± 1.4 | 94.3 ± 1.5 | 93.6 ± 1.4 | 94.6 ± 1.5 | |
p1 = 0.002 | p2 = 0.304 | p3 < 0.001 | p4 = 0.017 | |||
p5 = 0.341 | ||||||
PTV_elective | D2% [%] | 108.8 ± 5.2 | 105.7 ± 1.2 | 105.8 ± 1.2 | 106. ±1.1 | 105.1 ± 0.8 |
p1 = 0.008 | p2 = 0.272 | p3 = 0.001 | p4 < 0.001 | |||
p5 = 0.038 | ||||||
D98% [%] | 93.6 ± 1.8 | 92.8 ± 1.8 | 92.8 ± 2.1 | 91.4 ± 1.5 | 92.3 ± 1.8 | |
p1 = 0.077 | p2 = 0.986 | p3 < 0.001 | p4 < 0.001 | |||
p5 < 0.001 | ||||||
Mean [Gy] | 55.1 ± 0.6 | 54.4 ± 0.3 | 54.4 ± 0.4 | 54.4 ± 0.4 | 53.9 ± 0.3 | |
p1 < 0.001 | p2 = 0.701 | p3 = 0.366 | ||||
p5 < 0.001 | ||||||
Spinal Cord | Dmax [Gy] | 39.1 ± 7.3 | 32.0 ± 3.9 | 31.8 ± 3.9 | 33.1 ± 3.4 | 29.3 ± 3.2 |
p1 < 0.001 | p2 = 0.058 | p3 = 0.001 | p4 = 0.048 | |||
p5 = 0.001 | ||||||
Brain Stem | Dmax [Gy] | 37.9 ± 15.1 | 31.0 ± 13.4 | 31.1 ± 13.5 | 30.8 ± 13.5 | 29.8 ± 12.1 |
p1 = 0.023 | p2 = 0.757 | p3 = 0.864 | p4 = 0.515 | |||
p5 = 0.022 | ||||||
Oral Cavity | Mean [Gy] | 45.4 ± 9.3 | 40.2 ± 11.1 | 40.2 ± 11.0 | 41.3 ± 10.5 | 38.2 ± 10.2 |
p1 < 0.001 | p2 = 0.839 | p3 = <0.001 | p4 = 0.013 | |||
p5 < 0.001 | ||||||
Parotids | Mean [Gy] | 27.1 ± 6.0 | 24.9 ± 5.4 | 24.9 ± 5.2 | 25.2 ± 5.4 | 23.8 ± 4.9 |
p1 < 0.001 | p2 = 0.978 | p3 = 0.063 | p4 = 0.003 | |||
p5 < 0.001 | ||||||
Larynx | Mean [Gy] | 35.6 ± 7.4 | 25.7 ± 5.5 | 25.8 ± 5.6 | 26.9 ± 5.8 | 24.8 ± 5.2 |
p1 < 0.001 | p2 = 0.734 | p3 = 0.005 | p4 < 0.001 | |||
p5 < 0.001 | ||||||
Thyroid | Mean [Gy] | 45.6 ± 7.2 | 44.0 ± 6.6 | 44.1 ± 6.5 | 44.8 ± 6.4 | 42.0 ± 6.3 |
p1 = 0.094 | p2 = 0.542 | p3 < 0.001 | p4 < 0.001 | |||
p5 = 0.358 | ||||||
Eyes | Mean [Gy] | 3.9 ± 3.3 | 2.9 ± 1.6 | 3.0 ± 1.6 | 3.1 ± 1.5 | 2.8 ± 1.4 |
p1 = 0.036 | p2 = 0.618 | p3 = 0.253 | p4 = 0.229 | |||
p5 = 0.071 | ||||||
Constrictors | Mean [Gy] | 58.1 ± 12.3 | 55.2 ± 15.3 | 55.3 ± 15.2 | 55.7 ± 14.7 | 52.2 ± 14.6 |
p1 < 0.001 | p2 = 0.236 | p3 = 0.006 | p4 = 0.293 | |||
p5 < 0.001 | ||||||
Submandibulars | Mean [Gy] | 63.9 ± 6.3 | 63.8 ± 6.8 | 63.8 ± 6.8 | 63.9 ± 6.8 | 61.0 ± 5.4 |
p1 = 0.399 | p2 = 0.598 | p3 = 0.010 | p4 < 0.001 | |||
p5 = 0.866 | ||||||
(Body-PTV)/PTV | V_20Gy/V_PTV | 3.32 ± 0.48 | 2.74 ± 0.46 | 2.75 ± 0.47 | 2.67 ± 0.45 | 2.57 ± 0.44 |
p1 < 0.001 | p2 = 0.125 | p3 = 0.009 | ||||
p5 < 0.001 | ||||||
V_35Gy/V_PTV | 1.46 ± 0.28 | 1.07 ± 0.24 | 1.08 ± 0.24 | 1.07 ± 0.22 | 0.97 ± 0.21 | |
p1 < 0.001 | p2 = 0.002 | p3 = 0.881 | ||||
p5 < 0.001 |