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Table 2 Characteristics of preexisting GK series and this series in the treatment of iAN

From: Long-term follow-up after stereotactic radiosurgery of intracanalicular acoustic neurinoma

Authors, centre & year

n

Design

SRS System

FU (months)

Tumor control (no need for further treatment)

Preservation of hearing

CTCAE rating

Permanent CN VII impairment (%)

Pittsburgh, Ogunrinde et al. 1995 [22]

10

R, SC

GK

mean: 25 (3:64)

100%

80% (after one year)

no

0%

Pittsburgh, Niranjan et al. 1999 [23]

29

R, SC

GK

median: 33 (9;106)

100%

73%

no

0%

Pittsburgh, Niranjan et al. 2008 [10]

96

R, SC

GK

mean: 42 (12;144)

median: 28

99%

64.5%

no

2%

Marseille, Regis et al. 2011 [11]

34

P, SC

GK

mean: 44 (9;222)

97%

64% (after 5 years)

no

n/a

Seoul, Kim et al. 2012 [9]

58

R, SC

GK

mean: 62 (24;111)

100%

55% (after 5 years)

no

n/a

Cologne, this series, 2016

49

R, SC

LINAC

CK

mean: 65 (4;239)

median: 47

100%

75% (after 5 years)

yes

2%

  1. P prospective, R retrospective, SC single center