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Table 2 Characteristics of preexisting GK series and this series in the treatment of iAN

From: Long-term follow-up after stereotactic radiosurgery of intracanalicular acoustic neurinoma

Authors, centre & year n Design SRS System FU (months) Tumor control (no need for further treatment) Preservation of hearing CTCAE rating Permanent CN VII impairment (%)
Pittsburgh, Ogunrinde et al. 1995 [22] 10 R, SC GK mean: 25 (3:64) 100% 80% (after one year) no 0%
Pittsburgh, Niranjan et al. 1999 [23] 29 R, SC GK median: 33 (9;106) 100% 73% no 0%
Pittsburgh, Niranjan et al. 2008 [10] 96 R, SC GK mean: 42 (12;144)
median: 28
99% 64.5% no 2%
Marseille, Regis et al. 2011 [11] 34 P, SC GK mean: 44 (9;222) 97% 64% (after 5 years) no n/a
Seoul, Kim et al. 2012 [9] 58 R, SC GK mean: 62 (24;111) 100% 55% (after 5 years) no n/a
Cologne, this series, 2016 49 R, SC LINAC
CK
mean: 65 (4;239)
median: 47
100% 75% (after 5 years) yes 2%
  1. P prospective, R retrospective, SC single center