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Table 2 Univariate and multivariate analysis of risk factors for radiation induced rib fracture

From: Predictors of chest wall toxicity after stereotactic ablative radiotherapy using real-time tumor tracking for lung tumors

   Rib fracture p-value
Variables   No Yes Univariate Multivariate
Sex Male 26 4 0.493 NS
  Female 15 4   
Age ≤65 18 3 0.636 NS
  >65 23 5   
Tumor location Upper lobe 15 4 0.086 NS
  Lower lobea 26 4   
Multiple treatment No 24 5 0.759 NS
  Yes 17 3   
DM No 32 6 0.581 NS
  Yes 9 2   
COPD No 35 5 0.061 NS
  Yes 6 3   
GTV volume ≤17 cc 33 4 0.097 NS
  >17 cc 8 4   
Rib-tumor distance ≤0.4 cm 21 8 0.035 _
  >0.4 cm 20 0   
D4.6cc ≤140 Gy, EQD2 27 1 0.001 0.009
  >140 Gy, EQD2 21 7   
V160 ≤3.2 cc 27 0 0.000 _
  >3.2 cc 22 8   
  1. aincludes middle lobe in case of right lung
  2. DM diabetes mellitus, COPD chronic obstructive pulmonary disease, GTV gross tumor volume